彭屹峰,汤光宇,陈岳声,程爱萍,陈绍亮.衍射增强技术应用于医学成像的实验研究[J].中国医学影像技术,2007,23(7):1088~1091
衍射增强技术应用于医学成像的实验研究
Experiment study of DEI technique in medical imaging application
投稿时间:2006-12-26  修订日期:2007-05-07
DOI:
中文关键词:  衍射增强成像  相位衬度成像  同步辐射  摇摆曲线
英文关键词:Diffraction-enhanced imaging  Phase-contrast imaging  Synchrotron radiation  Rocking curve
基金项目:本课题受国家自然科学基金资助项目(30471652)。
作者单位E-mail
彭屹峰 同济大学附属第十人民医院放射科,上海 200072 peng2188@sina.com 
汤光宇 同济大学附属第十人民医院放射科,上海 200072  
陈岳声 同济大学附属第十人民医院放射科,上海 200072  
程爱萍 复旦大学附属中山医院影像医学研究所,上海 200032  
陈绍亮 复旦大学附属中山医院影像医学研究所,上海 200032  
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中文摘要:
      目的 本实验通过各类样品的DEI成像,获得衬度及分辨率,并与常规吸收成像比较,对衍射增强成像(DEI)方法进行分析和评价。方法 在北京高能物理研究所同步辐射装置(BSRF)形貌站(4W1A束线)上,取人及动物脏器在摇摆曲线上进行扫描,并与常规吸收像进行比较,通过显微放大法获得分辨率。结果 不同组织之间存在不同的衍射增强,DEI均显示较好的衬度和分辨率,图像分辨率达到微米级,并且扫描位置对图像显示具有较大影响。结论 DEI从相位衬度角度进行成像,极大地改进了成像质量,理论上来说是安全的,有望运用于临床。
英文摘要:
      Objective Through diffraction-enhanced imaging (DEI), contrast and resolution were obtained in all kinds of sample, and the imaging was compared with conventional imaging, then the DEI was analyzed and evaluated. Methods On the 4W1A line in the BSRF, human being and mouse viscera were imaged on rocking curve and the imaging was compared with conventional imaging, resolution was obtained by micro-magnify. Results There were different diffraction enhancing in different tissues; It was good contrast and resolution about the DEI of sample. The resolution reached to level of micron. And the scan location on rocking curve played significant influence on imaging quality. Conclusion The phase contrast imaging including DEI is an advanced imaging technique which images by phase-contrast mechanism, improving the imaging qualities greatly, and it is safe in theory, so it is hopeful for clinical medical application.
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