王宏,穆学涛,钟心.动态MRI和MSCT在肝硬化伴肝癌诊断中的比较研究[J].中国医学影像技术,2007,23(7):1046~1048 |
动态MRI和MSCT在肝硬化伴肝癌诊断中的比较研究 |
Comparative study of dynamic MRI and MSCT in hepatocellular carcinoma with cirrhosis |
投稿时间:2007-03-14 修订日期:2007-06-09 |
DOI: |
中文关键词: 磁共振成像 体层摄影术,X线计算机 肝硬化 肝细胞癌 |
英文关键词:Magnetic resonance imaging Tomography, X-ray computed Liver cirrhosis Hepatocellular carcinoma |
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中文摘要: |
目的 对比动态MRI和MSCT对肝硬化伴肝癌的敏感性,并用肝移植术后病理切片作对照。方法 73例肝硬化患者肝移植前90天内行MR和MSCT检查,所有患者检查前均不知其有无肝癌。MR扫描FLASH/T1WI、TSE/T2WI序列、动态3期增强扫描被获得。MSCT快流率注射对比剂优维显后行3期扫描;MR结果与MSCT相对照。结果 病理检查发现12例患者共20个肝癌,MRI发现其中12/20个肝癌,敏感性为60%,其中发现85.7%(6/7)的>2 cm的病变、46.2%(6/13)个≤2 cm的病变。MSCT发现11/20个肝癌,敏感性为55%,其中发现100%(7/7)的>2 cm的病变、30.8%(4/13)个≤2 cm的病变。对于肝癌的检出敏感性MRI与MSCT无差别。结论 MRI和MSCT对肝硬化伴肝癌的敏感性无显著差异,均可用于肝硬化病人移植前发现肝癌,但对小肝癌(≤2 cm)的敏感性仍需提高。 |
英文摘要: |
Objective To compare the sensitivity of dynamic MRI and multislice spiral CT(MSCT) for detection of hepatocellular carcinoma (HCC) by using explantation correlation in patients with cirrhosis. Methods Seventy-three cirrhosis patients without a known history of HCC who underwent MR and MSCT and subsequent liver transplantation within 90 days were examined. MSCT and MR with FLASH/T1WI, TSE/T2WI MR images were obtained. MR and MSCT images were obtained in the hepatic arterial, portal venous, and equilibrium phases. MRI interpretations were compared with MSCT. Results Twelve of seventy-three patients had 20 HCC. MRI depicted 12 of 20 HCC, for a sensitivity of 60%. MRI depicted 6 of 7 (85.7%) lesions larger than 2 cm, 6 of 13 (46.2%) lesions equal or smaller than 2 cm. MSCT depicted 11 of 20 HCC, for a sensitivity of 55%. MSCT depicted 7 of 7 (100%) lesions larger than 2 cm, 4 of 13(30.8%) lesions equal or smaller than 2 cm. The difference of sensitivity between MRI and MSCT was not statistically significant. Conclusion The difference of sensitivity between MR and MSCT was not statistically significant, but they are all insensitive for small (≤2 cm) HCC. |
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