| 金利芳,缪競陶,李征宇,解学乾,戴晓敏.多层螺旋CT体素指数评估慢性阻塞性肺病空气潴留的研究[J].中国医学影像技术,2007,23(7):1033~1036 |
| 多层螺旋CT体素指数评估慢性阻塞性肺病空气潴留的研究 |
| Study of voxel index from multislice CT in evaluating chronic obstructive pulmonary disease air-trapping |
| 投稿时间：2006-11-06 修订日期：2007-06-04 |
| DOI： |
| 中文关键词: 体层摄影术,X线计算机 体素 肺功能 空气潴留 慢性阻塞性肺病 |
| 英文关键词:Tomography, X-ray computed,Voxel Pulmonary function Air-trapping Chronic obstructive pulmonary disease |
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| 中文摘要: |
| 目的 探讨肺部多层螺旋CT(MSCT)体素指数(VI)在慢性阻塞性肺病(COPD)空气潴留定性、定量评估中的价值。方法 选取43例拟行胸部HRCT受检者行MSCT-DPVI,检查后1周内行肺功能测试。图像经后处理,分别设定呼吸双相的阈值,得到相应VI。各VI与PFT指标FEV1(%)、FEV1/FVC作统计学相关性分析,并通过ROC曲线找出界值。结果 所有VI与FEV1/FVC和FEV1(%)均具显著相关性(P<0.01)。与FEV1/FVC相关性最大的是呼气相VI-810(r=-0.606, P<0.01),其诊断界值是40%。与FEV1(%)相关性最大的是呼气相VI-790(r=-0.661, P<0.01)。结论 MSCT呼气相VI-810和呼气相VI-790可分别作为评估COPD空气潴留的定性指标和半定量指标。 |
| 英文摘要: |
| Objective To discuss the value of voxel index (VI) from multislice CT (MSCT) in qualitatively and quantitatively evaluating chronic obstructive pulmonary disease (COPD) air-trapping. Methods Forty-three subjects who were planned to take an HRCT scan of chest underwent MSCT dual phase volume imaging (MSCT-DPVI). Pulmonary function test was taken by all the subjects after MSCT-DPVI within the same week. By setting different CT values, different VI of inspiration phase and expiration phase were obtained from post processing. All the VI were compared statistically with PFT indexes FEV1(%) and FEV1/FVC, and the diagnose threshold value was found from ROC curve. Results All the VI were correlated with FEV1(%) and FEV1/FVC significantly (P<0.01). The VI most correlated with FEV1/FVC was expiratory VI-810 (r=-0.606, P<0.01), and its threshold value was 40%. The VI most correlated with FEV1(%) was expiratory VI-790(r=-0.661, P<0.01). Conclusion The expiratory VI-810 and expiratory VI-790 of MSCT can be used as qualitative index and semi-quantitative index respectively to evaluate COPD air-trapping. |
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