| 蔡崧,姜洪,崔兴宇,王大维,孙永涛.多层螺旋CT血管成像在下肢动脉硬化性闭塞症诊断中的应用[J].中国医学影像技术,2007,23(7):1022~1025 |
| 多层螺旋CT血管成像在下肢动脉硬化性闭塞症诊断中的应用 |
| Application of multi-slice spiral CT angiography in diagnosis of arteriosclerotic occlusive disease of lower extremity |
| 投稿时间：2007-03-05 修订日期：2007-06-25 |
| DOI： |
| 中文关键词: 体层摄影术,X线计算机 血管造影术 动脉硬化性闭塞症 |
| 英文关键词:Tomography, X-ray computed Angiography Arteriosclerotic occlusive disease |
| 基金项目:本研究为黑龙江省科技攻关计划立项课题(GC06C40701) |
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| 摘要点击次数: 1972 |
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| 中文摘要: |
| 目的 探讨多层螺旋CT血管成像诊断下肢动脉硬化性闭塞症的临床应用价值。方法 对同时接受16层CT血管成像和传统血管造影检查的279例患者进行回顾性分析,MSCTA重建采用最大密度投影(MIP) 、容积再现(VRT) 、曲面重建(CPR)、仿真内镜(VE) 等多种后处理方法。以DSA为"金标准",评价MSCTA诊断的准确性。结果 MSCTA诊断下肢动脉狭窄的敏感性为99.58%,特异性为96.85%,准确率为97.81%,阳性预测值为94.48%,阴性预测值为99.77%。MSCTA对有血流动力学意义的下肢动脉狭窄(血管狭窄程度≥50%)的检出敏感性为97.54%,特异性为98.12%,准确率97.98%。结论 多层螺旋CT血管成像诊断下肢动脉硬化性闭塞症有较高的敏感性、特异性和准确率,可部分替代DSA检查,为患者提供一种安全可靠的诊断方法,对临床治疗具有重要指导意义。 |
| 英文摘要: |
| Objective To evaluate the clinical value of multi-slice spiral CT angiography (MSCTA) in diagnosis of arteriosclerotic occlusive disease of lower extremity. Methods Two hundred and seventy-nine patients undergoing both 16-slice spiral CT angiography and conventional angiography were included in this reformation study. The data was reconstructed by maximum intensity projection, volume rendering technique, curved planar reconstruction and virtual endoscopy. Using DSA as the standard reference, the diagnostic accuracy of MSCTA was determined. Results In comparison with DSA, the sensitivity, specificity, accuracy, positive predictive value, and negative predictive value of MSCTA were 99.58%, 96.85%, 97.81%, 94.48%, and 99.77%, respectively. The sensitivity, specificity and accuracy of MSCTA with regard to detection of hemodynamically significant stenosis (≥50% luminal narrowing) were 97.54%, 98.12%, and 97.98%, respectively. Conclusion MSCTA has high sensitivity, specificity, and accuracy in detecting lower extremity arterial occlusive diseases and may partially substitute DSA examinations. MSCTAprovides another reliable diagnostic method for patients and has clinical importance for treatment. |
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