于治国,姚稚明,郑建国,屈婉莹.三磷酸腺苷介入心肌灌注断层显像对老年人冠心病的诊断价值[J].中国医学影像技术,2007,23(7):1002~1004
三磷酸腺苷介入心肌灌注断层显像对老年人冠心病的诊断价值
ATP stress myocardial perfusion tomographic imaging in detection of coronary disease in the elders
投稿时间:2007-02-05  修订日期:2007-06-21
DOI:
中文关键词:  腺苷三磷酸  心肌灌注  断层显像  冠心病
英文关键词:Adenosine triphosphate  Myocardial perfusion  Tomographic imaging  Coronary disease
基金项目:
作者单位E-mail
于治国 卫生部北京医院核医学科,北京 100730  
姚稚明 卫生部北京医院核医学科,北京 100730 yao.zhiming@163.com 
郑建国 卫生部北京医院核医学科,北京 100730  
屈婉莹 卫生部北京医院核医学科,北京 100730  
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中文摘要:
      目的 探讨三磷酸腺苷介入心肌灌注断层显像(ATP-MPI)诊断老年人冠心病(CAD)的价值和安全性。方法 49例无心肌梗死病史的老年冠心病待查患者(年龄≥60岁,平均年龄66.33岁)行ATP-MPI和冠状动脉造影(CAG)。结果 ATP介入试验过程中,共有19种不良反应表现,但这些表现均在停止注射ATP后2分内自行终止,无一例病人因不良反应中断ATP介入试验。ATP-MPI诊断老年人冠心病的敏感性90.0%,特异性89.5%,准确性89.8%;诊断冠状动脉狭窄的敏感性84.1%,特异性90.1%。结论 ATP介入心肌灌注断层显像是诊断老年冠心病准确性和安全性均很高的无创检查方法。
英文摘要:
      Objective To evaluate the value and safety of ATP stress myocardial perfusion tomographic imaging in detection of coronary disease (CAD) in the elders. Methods Forty-nine patients ≥60 years old without myocardial infarction were included in the research. All patients underwent ATP-MPI and coronary angiography within 2 months. Results There were 19 kinds of side effects occur during ATP stress. However, no ATP stress was interrupted by the side effects, and no patients needed special therapy on the side effects. The sensitivity, specificity and accuracy of ATP stress in detection of coronary artery disease were 90.0%, 89.5%, and 89.8%, respectively. Conclusion ATP stress myocardial perfusion tomography imaging is a good noninvasive method with high diagnostic accuracy and safety in detection of coronary artery disease in the elders.
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