| 流泉,王新疆,赵锡海,张涛,李力兵,蔡幼铨,马林.心肌纤维束DTI的实验研究程[J].中国医学影像技术,2007,23(5):649~651 |
| 心肌纤维束DTI的实验研究程 |
| Experimental study of myocardial fiber architecture using DTI technique |
| 投稿时间：2006-11-16 修订日期：2007-03-27 |
| DOI： |
| 中文关键词: 心肌纤维 磁共振成像 弥散张量成像 |
| 英文关键词:Myocardial fiber Magnetic resonance imaging Diffusion tensor imaging |
| 基金项目:本研究受全军医药卫生科研项目资助(06Q069)。 |
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| 中文摘要: |
| 目的 尝试使用MR弥散张量成像(DTI)显示离体心肌纤维束结构的可能性。方法 使用25个方向的DTI序列扫描离体1 h和24 h的猪心脏,使用脑白质纤维束成像重建方式显示心肌纤维的走行、分布和排列方式。结果 DTI可以清晰显示离体1 h心肌的排列特征为分层、螺旋、扭转和发散,与广义上心肌纤维的排列方式吻合;离体24 h后由于心肌发生溶解,DTI显示的心肌纤维的完整性被破坏,表现为心肌纤维长度缩短、外形皱缩、排列扭曲。结论 DTI技术可以显示离体心肌纤维的完整性和排列方式,其潜在的应用领域为心肌纤维的形态功能的试验研究。 |
| 英文摘要: |
| Objective To investigate the feasibility of MR diffusion tensor imaging (DTI) technique in displaying myocardial fiber architecture. Methods On an ex vivo swine heart, DTI was acquired in 25 directions 1 hour and 24 hours after excision. The myocardial fiber was reconstructed using brain white matter tractography algorithm to display its course, distribution and arrangement. Results On the heart 1 hour after excision, DTI revealed the arrangement of the myocardial fiber showing laminar, helix, twist and dispersal patterns, which is consistent with the array of the myocardial fiber in general anatomical descriptions. After 24 hours, because of the myocardium dissolving, DTI revealed the disintegration of the myocardial fiber, showing shortening, shrinking and distortion. Conclusion MR DTI could reveal the myocardial fiber architecture, showing its integrity and arrangement. It has potential in the study of myocardial structure-function. |
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