| 薛雁山,胡玉川,尚存海,李红梅,田桂琴.肝硬化肠病多层螺旋CT灌注初步研究[J].中国医学影像技术,2007,23(4):562~565 |
| 肝硬化肠病多层螺旋CT灌注初步研究 |
| Multi-slice CT perfusion study on intestinopathy with cirrhosis |
| 投稿时间：2006-09-14 修订日期：2007-04-03 |
| DOI： |
| 中文关键词: 肝硬化 灌注 血流动力学过程 体层摄影术,X线计算机 |
| 英文关键词:Liver cirrhosis Perfusion Haemodynamic processes Tomography, X-ray computed |
| 基金项目:本研究为山西省高校研发项目(2006211)。 |
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| 摘要点击次数: 2019 |
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| 中文摘要: |
| 目的 探讨不同程度肝硬化患者小肠血流动力学变化。方法 20例正常对照组和47例肝硬化病例组患者,其中代偿期肝硬化(CC)18例,失代偿期肝硬化(DCC)29例,用16层螺旋CT行十二指肠同层序列动态增强检查。CT后处理得出血流量(BF)、血容量(BV)、对比剂平均通过时间(MTT)和渗透表面积乘积(PS)灌注参数。统计分析这些参数。结果 正常对照组、CC组及DCC组间的BF、MTT,总体上具有显著性差异 。DCC组BF值明显降低、MTT值明显延长,与另两组两两比较差异均具有统计学意义。各组的BV和PS在总体上差别无统计学意义(BV值: 对照组(8.69±3.69) ml/100 g, CC组(9.21±7.50) ml/100 g, DCC组(7.16±3.58) ml/100 g;P＞0.05。PS值:对照组(18.01±1.90) ml/(100g·min), CC组(10.32±2.84) ml/(100g·min), DCC组(19.62±2.64) ml/(100g·min) ,P＞0.05]。结论 多层螺旋CT灌注成像可用于评价不同程度肝硬化患者小肠血流动力学变化。 |
| 英文摘要: |
| Objective To evaluate hemodynamics changes of small intestine in patients with different severities liver cirrhosis. Methods Dynamic contrast-enhanced single-location sequences CT scan of duodenum was performed in 20 control subjects (CS) and 47 patients with liver cirrhosis in which 18 cases with compensated cirrhosis (CC) and 29 cases with decompensated cirrhosis (DCC), respectively, proven by clinical and laboratory examinations. Perfusion parameters such as blood flow (BF)、blood volume(BV)、mean transit time (MTT) and permeability surface area product (PS) were calculated and analysis. Results The BF and MTT parameters between groups were significantly differences . There were remarkable differences between DCC and any other two groups on the BF and MTT. BV and PS didn't change obviously among all groups . Conclusion Multi-slice CT perfusion imaging can evaluate to intestinal hemodynamic changes in patient with different severities liver cirrhosis. |
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