| 何云,李智贤,廖新红,梁淡媚,杨红.超声引导经皮肝穿在婴儿肝炎综合征诊断中的临床应用价值[J].中国医学影像技术,2007,23(2):262~264 |
| 超声引导经皮肝穿在婴儿肝炎综合征诊断中的临床应用价值 |
| Percutaneous liver biopsy guided by ultrasound in infant hepatic syndrome |
| 投稿时间：2006-09-15 修订日期：2006-11-12 |
| DOI： |
| 中文关键词: 婴儿肝炎综合征 经皮肝穿活检 超声引导 |
| 英文关键词:Infant hepatitis syndrome Percutaneous liver biopsy Ultrasound guided |
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| 中文摘要: |
| 目的 探讨超声引导经皮肝穿活检在婴儿肝炎综合征(IHS)的应用价值。方法 按全国小儿病毒性肝炎防治座谈会制定的标准诊断为IHS的患儿37例,全部病例有黄疸、肝大或肝脾大及肝功能损害。在超声引导下使用自动活检枪弹射18G配枪用槽式切割活检针,彩超引导避开肝内血管及胆管、胆囊等重要结构,肝组织标本采用HE染色及马松染色。结果 IHS主要病理特征以肝纤维结缔组织增生最常见,其他依次为肝细胞水变性、肝细胞点状、灶性坏死、碎片状坏死、淤胆、巨细胞形成、肝小叶结构紊乱等;37例中35例存在不同程度肝纤维化,年龄≤6个月29例,其中S1 7例,S2 4例,S3 11例,S4 13例。结论 采用实时超声引导下婴儿经皮肝组织自动活检术是一项安全、快速、成功率高、并发症少的技术,能为婴儿这一特殊年龄组肝脏疾病的诊断提供更多更新的信息。 |
| 英文摘要: |
| Objective To explore the application value of percutaneous liver biopsy guided by ultrasound in infants with infant hepatitis syndrome (IHS). Methods Percutaneous liver biopsy guided by ultrasound was carried out in 37 clinical diagnosed infants with IHS. All the infants were presented with jaundice, hepatomegaly, splenomegaly or liver function damage. Color Doppler ultrasonography was performed to avoid the injure of the blood vessel and bile duct during the procedure, the biopsy specimens were stained with routine hematoxylin and eosin (HE) or special dyed method for fibrosis such as Masson trichrome. Results The main histological features of IHS were hepatic fibrosis, followed by hepatocyte watery degeneration, punctuate, dotted and piecemeal necrosis, bile plugs, accumulation of macrophage, structure disorders of liver lobules. 35 cases among the 37 IHS existed the different stages of fibrosis: 7 cases of stage 1 (S1), 4 of S2, 11 of S3, and 11 of S4. Conclusion The technique of percutaneous automatic biopsy guided by ultrasound is a safe, rapid and effective method with high successful rate and low complication rate, the accurate rate for diagnosis of liver diseases was remarkably improved through this method, and thus deserved to be used clinically and broadly. |
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