张铁宁,张皓,缪竞陶.MR灌注成像在肝脏常见占位性病变诊断及鉴别诊断中的价值初探[J].中国医学影像技术,2006,22(12):1849~1852
MR灌注成像在肝脏常见占位性病变诊断及鉴别诊断中的价值初探
MR perfusion imaging in the diagnosis and differential diagnosis of common liver masses: preliminary study
投稿时间:2006-05-15  修订日期:2006-09-26
DOI:
中文关键词:  磁共振成像  灌注  肝占位
英文关键词:Magnetic resonance imaging  Perfusion  Liver masses
基金项目:
作者单位E-mail
张铁宁 上海交通大学附属第一人民医院肿瘤科,上海 200080  
张皓 上海交通大学附属第一人民医院放射科,上海 200080 zhanghao021@gmail.com 
缪竞陶 上海交通大学附属第一人民医院放射科,上海 200080  
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中文摘要:
      目的 探讨MR灌注成像在肝脏常见占位性病变诊断以及鉴别诊断中的价值。方法 对49例患者共84个病灶行双层2D FSPGR序列MR灌注成像检查(其中28个原发性肝细胞癌、22个转移性肝癌、19个肝血管瘤、15个肝脓肿病灶)。根据对比剂首过期内的原始图像,获取每个病灶的时间-信号强度曲线(TIC),记录病灶的峰值时间(TP),计算肝脏灌注指数(HPI)。结果 各组肝占位性病变的TP差异没有统计学意义。各占位病变组的HPI均高于正常肝组织组。原发性肝癌的HPI的明显高于转移性肝癌、肝血管瘤及肝脓肿的HPI。转移性肝癌、肝血管瘤、肝脓肿的HPI之间无显著性差异。结论 MR灌注成像有助于常见肝占位性病变的诊断和鉴别诊断。
英文摘要:
      Objective To evaluate the value of MR perfusion imaging in the diagnosis and differential diagnosis of common liver masses. Methods Forty-nine patients with 84 hepatic masses (28 hepatic cell carcinomas, 22 metastases, 19 hemangiomas and 15 liver abscesses) underwent liver MR perfusion imaging by using a double slice 2D FSPGR sequence. From the original images during first-pass of contrast bolus, time-intensity curve (TIC) of each mass were got. The time to peak (TP) of each mass was recorded and hepatic perfusion indexes (HPI) were calculated. Results No statistic significances of TP were found among different groups of liver masses. The HPIs of hepatocellular carcinoma, metastasis, hemangioma and liver abscess were significantly higher than normal liver tissue. The HPI of HCC was higher than metastasis, hemangioma and abscess. The HPIs of liver metastasis, hemangioma and abscess showed no statistical significance. Conclusion MR perfusion imaging is helpful for the diagnosis and differential diagnosis of common liver masses.
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