| 高思佳,刘静红,梁传声,张妍芬,王忠辉,石强,徐克.CT灌注成像在颅内-外动脉狭窄脑缺血诊断中的临床应用[J].中国医学影像技术,2006,22(11):1656~1658 |
| CT灌注成像在颅内-外动脉狭窄脑缺血诊断中的临床应用 |
| Perfusion CT on intra and extracranial arteries stenosis ischemia |
| 投稿时间：2006-07-16 修订日期：2006-09-18 |
| DOI： |
| 中文关键词: 灌注,局部 体层摄影术,X线计算机 脑缺血 颈动脉狭窄 |
| 英文关键词:Perfusion, regional Tomography, X-ray computed Brain ischemia Carotid stenosis |
| 基金项目:辽宁省教育厅高等学校科学研究项目基金(05L453)。 |
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| 中文摘要: |
| 目的 探讨CT灌注成像对脑缺血病变的诊断价值。方法 经CTA或DSA检查诊断颅内或颅外动脉狭窄并作CT灌注成像检查的病人51例,男45例,女6例,平均52岁。临床症状多为头晕、肢体无力、言语不清、复视、TIA发作。CT扫描方法为CT颅脑平扫、CT灌注扫描及头颈部CTA。CT灌注后处理分别得出CBF图、 CBV图、MTT图及TTP伪彩功能图。结果 11例CT或MRI表现为非责任病灶的多发性腔隙性脑梗死,余病例常规CT或MRI无异常所见。17例CT灌注各参数图未见缺血改变,34例病例均存在不同程度的缺血改变。所有病例均表现为rMTT延长,rCBF降低,均数rMTT为3.14±1.02,rCBF为0.46±0.16, rTTP为1.28±0.11;其中 21例rCBV升高,均数为1.48±0.19;6例rCBV降低,均数为0.76±0.05;7例rCBV接近正常,均数为1.03±0.05。结论 CT灌注成像能清楚显示常规CT、MRI不能显示的异常脑血流灌注,是一种很好的反映脑缺血改变的影像学检查方法。 |
| 英文摘要: |
| Objective To explore the diagnostic value of CT perfusion imaging on cerebral ischemia. Methods Fifty-one patients with intra- or extracranial arteries stenosis diagnosed by CTA or DSA were performed CT perfusion imaging involved 45 males and 6 females, average 52 years old. Clinical symptoms included dizziness, extremity adynamia, barylalia, diplopia, TIA et al. CT scan method: cranial routine CT scan, CT perfusion and CTA. With CT perfusion software, CBF, CBV and MTT color maps were generated. Results Eleven presented with non-responsible multi lacunar infarction and the others are normal by CT or MRI. Every CT perfusion parameter map showed no ischemia changes in 17 patients, otherwise, showed ischemia in various degrees in the other patients. rMTT value of all patients delayed and rCBF value descend, rMTT 3.14±1.02, rCBF 0.46±0.16 and rTTP 1.28±0.11. rCBV of 21 patients ascended, average 1.48±0.19; rCBV of 6 patients descended, average 0.76±0.05; and rCBV of 7 patients were normal, average 1.03±0.05. Conclusion CT perfusion imaging is an effective examination method for cerebral ischemic changes, which can clearly presents the abnormal hemodynamics that routine CT、MRI can't display. |
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