| 郑奎宏,马林,郭勇,林伟,黄敏华,张燕群,赵书臣,钱明珠,梁英魁,陶丽冰.克-亚二氏综合征的MR表现[J].中国医学影像技术,2006,22(10):1554~1557 |
| 克-亚二氏综合征的MR表现 |
| MRI features of Creutzfeldt-Jakob disease |
| 投稿时间：2006-03-30 修订日期：2006-08-04 |
| DOI： |
| 中文关键词: 克-亚二氏综合征 磁共振成像 扩散加权成像 |
| 英文关键词:Creutzfeldt-Jakob disease Magnetic resonance imaging Diffusion-weighted imaging |
| 基金项目: |
| 作者 | 单位 | E-mail | | 郑奎宏 | 海军总医院放射科,北京 100037 | zhengkuihong@vip.sina.com.cn | | 马林 | 解放军总医院放射科,北京 100853 | | | 郭勇 | 海军总医院放射科,北京 100037 | | | 林伟 | 海军总医院放射科,北京 100037 | | | 黄敏华 | 海军总医院放射科,北京 100037 | | | 张燕群 | 海军总医院放射科,北京 100037 | | | 赵书臣 | 海军总医院放射科,北京 100037 | | | 钱明珠 | 海军总医院放射科,北京 100037 | | | 梁英魁 | 海军总医院放射科,北京 100037 | | | 陶丽冰 | 海军总医院放射科,北京 100037 | |
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| 中文摘要: |
| 目的 描述克-亚二氏综合征的脑部MRI表现,探讨MRI对该病的诊断价值。方法 经病理证实的克-亚二氏综合征4例,回顾性分析其MRI和扩散加权像(DWI)表现,并复习相关临床及文献资料。结果 1例表现为双侧脑室旁深部白质区及内囊后肢皮质脊髓束走行区稍长T1、稍长T2信号;2例T2WI及DWI上表现为双侧尾状核和壳核区对称性稍高信号影和部分皮质带状异常高信号;1例T2WI及DWI上表现为部分皮质带状异常高信号,伴脑萎缩。结论 克-亚二氏综合征的脑部MRI表现有比较典型的特点,MRI是诊断该病的重要手段。 |
| 英文摘要: |
| Objective To describe MR imaging findings of the brain in Creutzfeldt-Jakob disease (CJD), and to evaluate the diagnostic usefulness of MRI in CJD. Methods Four patients with biopsy proved CJD were reviewed. The imaging findings on conventional MRI and diffusion-weighted imaging (DWI) were retrospectively analyzed. The clinical symptoms and literature were also reviewed. Results Bilateral high signal intensity on T2-weighted images in the deep white matter and corticospinal tracts was demonstrated in one case. In 2 cases, the symmetrical hyperintensities in the caudate nuclei and putamen were revealed and ribbon-like abnormalities in the cerebral cortex were showed on both T2-weighted and diffusion-weighted images. In one case, the ribbon-like abnormalities in the cerebral cortex were showed on both T2-weighted and diffusion-weighted images. Pronounced cerebral atrophy with widened sulci was also seen on MRI. Conclusion CJD has some characteristic appearance on MRI, and therefore MRI is of great value in diagnosing the disease. |
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