高莉,付占立,王继琛,孙晓伟,邱建星,刘建新,蒋学祥.64层螺旋CT心肌早期低灌注改变诊断心肌梗死——与SPECT的对比研究[J].中国医学影像技术,2006,22(10):1460~1463
64层螺旋CT心肌早期低灌注改变诊断心肌梗死——与SPECT的对比研究
Early low contrast enhancement in diagnosis of myocardial infarction with 64-slice spiral CT: comparison with SPECT
投稿时间:2006-07-17  修订日期:2006-09-23
DOI:
中文关键词:  体层摄影术,X线计算机  单光子发射型计算机断层摄影术  心肌梗死
英文关键词:Tomography, X-ray computed  Single photon emission computed tomography  Myocardial infarction
基金项目:
作者单位E-mail
高莉 北京大学第一医院医学影像科,北京 100034 gaoli_xue@yahoo.com.cn 
付占立 北京大学第一医院医学影像科,北京 100034  
王继琛 北京大学第一医院医学影像科,北京 100034  
孙晓伟 北京大学第一医院医学影像科,北京 100034  
邱建星 北京大学第一医院医学影像科,北京 100034  
刘建新 北京大学第一医院医学影像科,北京 100034  
蒋学祥 北京大学第一医院医学影像科,北京 100034  
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中文摘要:
      目的 对比较核素心肌灌注检查结果,评价后心电门控的64层螺旋CT早期低灌注改变诊断心肌梗死的价值。方法 以SPECT结果为标准,将10位患者的188段心肌分为5组(正常组,灌注轻度减淡组,灌注中度减淡组,灌注重度减淡组和灌注缺损组),对不同分组的心肌CT值进行统计学分析。采用受试者操作特性ROC曲线获取心肌低灌注改变诊断心肌梗死的最佳阈值。结果 正常组心肌CT值与梗死各组心肌CT值之间有显著差异(P<0.01)。以65 Hu作为诊断心肌梗死的阈值,CT诊断的敏感性为91.8%,特异性为 79.9%。结论 64层螺旋CT早期低灌注改变可以准确地诊断心肌梗死改变,并可进行定量分析。
英文摘要:
      Objective To assess the diagnostic value of contrast enhanced CT with retrospectively ECG-gating in the detection of myocardial infarction, comparison with the results of single photon emission computed tomography (SPECT). Methods 188 segments myocardium of 10 patients were studied with contrast-enhanced retrospectively ECG-gated CT. Reformatted short-axis images were assessed for myocardial perfusion deficits. Perfusion deficits were compared with the score of SPECT by using one-way ANOVA analysis and ROC analysis of variance. Results There was significant difference between infracted myocardium and normal myocardium at CT attenuation (P<0.01). Regarding 65 Hu as the diagnostic standard of myocardial infarction, the sensitivity was 91.8%, the specificity was 79.9%. Conclusion The changes of early low contrast enhancement permit the detection and quantitatively characterization of myocardial infarction.
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