| 李凡,杜联芳,邢晋放.超声造影剂对肾动静脉通过时间的初步研究[J].中国医学影像技术,2006,22(9):1399~1401 |
| 超声造影剂对肾动静脉通过时间的初步研究 |
| Ultrasound contrast-enhanced agent in renal arteriovenous transit time: a preliminary study |
| 投稿时间：2006-06-15 修订日期：2006-08-10 |
| DOI： |
| 中文关键词: 超声检查,造影剂 肾动静脉通过时间 肾功能 |
| 英文关键词:Ultrasonography, contrast agent Renal arteriovenous transit time Renal function |
| 基金项目:本课题受上海市卫生局科学技术发展基金资助(044010)。 |
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| 中文摘要: |
| 目的 研究超声造影剂SonoVue在正常人的肾动静脉通过时间(RAVTT),以及比较RAVTT在肾功能正常者与异常(慢性肾病2期)患者间的差异,探讨其评价肾功能的价值。方法 对69例成人肾脏进行常规超声和超声造影检查,病例组42例(包括肾脏有良、恶性占位的患者及慢性肾病2期患者,分别为7例、25例和10例),正常对照组27例。常规超声观测肾脏后经肘静脉团注SonoVue,造影结束后用ACQ分析软件对各组肾门处肾动、静脉主干内造影剂达到时间进行测定和差值分析。结果 正常人RAVTT在年龄组间的差异无统计学意义;肾脏有良、恶性占位患者与正常人的RAVTT差异亦无统计学意义;慢性肾病2期患者的RAVTT明显延长为(4.39±0.37)s,与上述各组差异显著(P<0.05)。结论 SonoVue在正常人的RAVTT为(2.70±0.16)s,这为今后RAVTT的研究提供了参考标准。RAVTT在慢性肾病2期的患者为(4.39±0.37)s。RAVTT通过敏感反映肾脏血流量及流速的信息可初步评估肾功能。 |
| 英文摘要: |
| Objective To study the renal arteriovenous transit time (RAVTT) of ultrasound contrast agent (SonoVue) in healthy adults, and to discuss the value of RAVTT in evaluating renal function by comparing the time between patients with normal or abnormal renal function (2 stage of nephropathy). Methods Sixty-nine patients were examined by baseline ultrasonography, and underwent contrast-enhanced ultrasonography, after injection of SonoVue into the ulnar vein, then the arrival time (AT) of the contrast echoes in the renal portal artery and renal portal vein was analyzed. Results There was no significant difference of RAVTT between healthy adult group and patients group with renal benign or malignant space-occupying lesion. However, RAVTT of patients with 2 stage of nephropathy was distinctively longer (4.39±0.37 s) than that of the normal patients (P<0.05). RAVTT≤4 s was found in all patients with normal renal function. Conclusion RAVTT of SonoVue in healthy adults is (2.70±0.16) s, which provide a reference for following study. RAVTT in patients group with 2 stage of nephropathy is (4.39±0.37) s. Renal arteriovenous transit time measurement could be used to preliminarily evaluate renal function by offering volume and velocity information of renal blood flow. |
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