| 王海燕,赵斌,王光彬.磁共振扩散张量成像在显示正常人脑白质纤维中的应用[J].中国医学影像技术,2006,22(9):1325~1329 |
| 磁共振扩散张量成像在显示正常人脑白质纤维中的应用 |
| Visualizing white matter fiber structure in human brain using diffusion tensor imaging |
| 投稿时间：2006-02-24 修订日期：2006-07-30 |
| DOI： |
| 中文关键词: 磁共振成像 扩散张量成像 纤维跟踪技术 白质 |
| 英文关键词:Magnetic resonance imaging Diffusion tensor imaging Tractography White matter |
| 基金项目: |
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| 中文摘要: |
| 目的 应用DTI技术显示正常人脑白质纤维,探讨其与解剖学描述的一致性。方法 20名健康志愿者行颅脑MRI与颅脑单次激发回波平面扩散张量成像扫描(b值=0,500 s/mm2),在Siemens Leonardo工作站应用纤维束跟踪软件(Siemens Standar 12 dirs)进行后处理重建出白质纤维束。结果 对主要白质纤维如皮质脊髓束、皮质核束、胼胝体、扣带、上纵束、下纵束、上枕额束、下枕额束、钩束进行模拟显示,不同纤维需要选择适合的感兴趣区、各向异性阈值、角度阈值、步长和体素内采样数目等参数,显示结果与解剖学描述具有较好的一致性。结论 利用扩散张量成像技术可模拟显示正常人脑白质纤维,与解剖学描述具有较好的一致性,是在活体中研究人脑白质纤维的一种较可靠的方法。 |
| 英文摘要: |
| Objective To visualize the matter fibers of human brain by diffusion tensor MR imaging, and to investigate the consistency between the imaging and anatomic descriptions. Methods Twenty healthy volunteers were examined by MRI and single shot echo-planar diffusion tensor imaging (b=0, 500 s/mm2), post processing were made in SIEMENS Leonardo workstation using SIEMENS Standar 12 dirs software to reconstruct the white matter fibers. Results Visualizing the white matter fibers of human brain such as, corticospinal tract, corticobulbar tract, corpus callosum, cingulum, superior longitudinal fasciculus, inferior longitudinal fasciculus, superior fronto-occipital fasciculus, inferior fronto-occipital fasciculus, uncinate fasciculus. Each fiber need selecting appreciative regions of interest (ROI) and FA threshold, angle threshold, step length and number of sampling in a voxel size. The images shown on diffusion tensor tractography was well consistent with the anatomic features. Conclusion The white matter of human brain could be visualized by diffusion tensor imaging in vitro, with the imaging features being well consistent with anatomic descriptions. Diffusion tensor imaging is a reliable method to study the white matter fibers of human brain. |
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