| 卢洁,李坤成,高艳,焦立群,李萌.氙CT评价颈内和大脑中动脉狭窄或闭塞的脑血流研究[J].中国医学影像技术,2006,22(9):1317~1320 |
| 氙CT评价颈内和大脑中动脉狭窄或闭塞的脑血流研究 |
| Study on cerebral blood flow in patients with ICA/MCA stenosis or occlusion by Xenon CT |
| 投稿时间：2006-05-06 修订日期：2006-08-02 |
| DOI： |
| 中文关键词: 颈内动脉 大脑中动脉 狭窄,闭塞 脑血流量 氙 体层摄影术,X线计算机 |
| 英文关键词:Internal carotid artery Middle cerebral artery Stenosis, occlusion Cerebral blood flow Xenon Tomography, X-ray computed |
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| 中文摘要: |
| 目的 探讨颈内/大脑中动脉慢性狭窄、闭塞患者的氙CT脑血流成像表现及其临床应用价值。方法 20例颈内/大脑中动脉慢性重度狭窄或闭塞患者行氙CT脑血流成像检查,2例行乙酰唑胺负荷试验。计算出脑血流图,进行定性和定量分析。结果 20例颈内/大脑中动脉慢性重度狭窄或闭塞患者,10例单侧ICA/MCA重度狭窄或闭塞患者,7例发现病变侧CBF轻度下降,但无显著性差异(P>0.05)。10例单侧ICA/MCA闭塞,对侧重度狭窄患者,9例CBF图发现异常改变,表现为闭塞侧CBF下降较狭窄侧降低明显(P<0.05);闭塞侧CBF值与单侧病变患者的正常侧比较有显著性差异(P<0.05)。2例行乙酰唑胺负荷试验患者,负荷后CBF降低较负荷前明显。结论 氙CT检查能够显示颈内/大脑中动脉慢性重度狭窄或闭塞脑血流情况,有利于临床的诊断和治疗。 |
| 英文摘要: |
| Objective To investigate the diagnostic value of XeCT in patients with ICA/MCA high-grade stenosis or occlusion. Methods XeCT was performed in 20 patients with ICA/MCA high-grade stenosis or occlusion. The cerebral blood flow (CBF) was measured, the qualitative and quantitative analysis were carried out on bilateral hemisphere. Results In 10 cases of unilateral ICA/MCA high-grade stenosis or occlusion, CBF changes corresponding to clinical symptoms were found in 7 cases, but the value of CBF had no statistical difference between affected side and contralateral side(P>0.05). In 10 cases of bilateral ICA/MCA high-grade stenosis or occlusion, CBF changes corresponding to clinical symptoms were found in 9 cases, the value of CBF had statistically significant difference between affected side and contralateral side(P<0.05). Conclusion XeCT could provide qualitative and quantitative changes of CBF in patients with bilateral ICA/MCA high-grade stenosis or occlusion and thereby it was helpful for the diagnosis and therapy. |
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