| 金蓉,李彦敏,崔壮,焦彤,高卫平.卵巢肿瘤的彩色血管能量成像与微血管密度的相关性研究[J].中国医学影像技术,2006,22(7):1064~1066 |
| 卵巢肿瘤的彩色血管能量成像与微血管密度的相关性研究 |
| Correlation study between color power angio imaging and microvessel density on ovarian tumors |
| 投稿时间：2006-01-05 修订日期：2006-04-27 |
| DOI： |
| 中文关键词: 卵巢肿瘤 彩色血管能量成像 微血管密度 |
| 英文关键词:Ovarian tumors Color power angio imaging Microvessel density |
| 基金项目:本课题受天津市自然科学基金资助(033609011)。 |
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| 中文摘要: |
| 目的 探讨卵巢肿瘤的彩色血管能量成像(CPA)与病理微血管密度(MVD) 的相关性及其临床价值。方法 50例卵巢肿瘤患者术前应用CPA技术检测其血流,测其血流的阻力指数RI,术后对手术标本行免疫组化染色,计算MVD,行其统计学相关性对比分析。结果 卵巢恶性肿瘤的MVD(48.84±6.19)显著高于良性卵巢肿瘤(20.90±2.71, P<0.05),恶性肿瘤中CPAⅢ级的MVD(50.37±5.46)显著高于Ⅱ级(32.11±3.71,P<0.05)。良、恶性卵巢肿瘤的MVD与CPA的血流分级呈正相关(r=0.455, r=0.823, P<0.05)。卵巢恶性肿瘤的RI值(0.36±0.06)显著低于良性卵巢肿瘤(0.68±0.07,P<0.05),RI值与MVD呈负相关(r=-0.806, P<0.05)。结论 病理形态学基础表明,CPA在诊断良、恶性卵巢肿瘤中有重要的临床价值。 |
| 英文摘要: |
| Objective To discuss the relationship between color power angio imaging and microvessel density of ovarian tumors. Methods Fifty ovarian tumors were examined preoperatively by CPA and resistance index (RI) values were recorded for assessment. Their microvessels were stained immunohistochemically after operation. Results Microvessel density (MVD) in ovarian carcinomas (48.84±6.19) was higher than that in benign tumors (20.90±2.71, P<0.05). MVD of CPA Ⅲ (50.37±5.46) was higher than that in CPA Ⅱ (32.11±3.71, P<0.05). The MVD values of benign and malignant ovarian tumors demonstrated a positive correlation to the degrees of CPA (r=0.455, r=0.823, P<0.05). The RI values of malignant group (0.36±0.06) was significantly lower than that of the benign group (0.68±0.07, P<0.05). RI values and MVD showed negative correlation (r=-0.806, P<0.05). Conclusion The results obtained in this study may provide valuable information in clinic in distinguishing benign from malignant ovarian tumors with the color power angio imaging. |
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