杨颖,陈峰,张宝娓,齐丽彤,赵锋,何萍.二维应变对左心室整体应变与应变率的研究[J].中国医学影像技术,2006,22(7):1018~1020
二维应变对左心室整体应变与应变率的研究
Two-dimensional strain in evaluation of global left ventricular strain and strain rate
投稿时间:2006-01-24  修订日期:2006-03-22
DOI:
中文关键词:  二维应变  应变率  心室功能,左
英文关键词:Two-dimensional strain  Strain rate  Ventricular function, left
基金项目:
作者单位E-mail
杨颖 北京大学第一医院心血管内科,北京 100034 yangcherry@sohu.com 
陈峰 北京大学第一医院心血管内科,北京 100034  
张宝娓 北京大学第一医院心血管内科,北京 100034  
齐丽彤 北京大学第一医院心血管内科,北京 100034  
赵锋 北京大学第一医院心血管内科,北京 100034  
何萍 北京大学第一医院心血管内科,北京 100034  
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中文摘要:
      目的 评价新的超声软件二维应变(2DS)用于定量左心室整体应变与应变率的可行性与价值。方法 采集21例心衰患者与15例正常对照者心尖二腔、三腔、四腔长轴与乳头肌水平短轴二维灰阶动态图。采用心尖双平面Simpson法测量左室射血分数(EF)。应用2DS软件由心尖长轴图像测量左室长轴收缩峰值应变(GSL)与应变率(GSrL);乳头肌短轴图像测量左室轴向收缩峰值应变(GSC)与应变率(GSrC)。比较心衰组与对照组各参数测值,分析EF与应变及应变率参数相关性。结果 心衰组GSL、GSrL、GSC及GSrC均显著低于正常组(P<0.001)。EF与GSL、GSrL、GSC及GSrC均有良好的相关性(r=0.88,0.87,0.85,0.83)。结论 2DS可用于定量左室整体应变与应变率,有望成为客观准确定量左室功能的新方法用于临床。
英文摘要:
      Objective To assess the feasibility and value of two-dimensional strain (2DS), a novel software for quantitative echocardiographic assessment of global left ventricular (LV) strain and strain rate. Methods Two-dimensional echocardiography was performed in 21 patients with heart failure and 15 normal control subjects. LV ejection fraction (EF) was calculated through bi-plane Simpson's rule. Global longitudinal peak systolic strain (GSL) and strain rate (GSrL) were measured by 2DS from apical 2-chamber, 3-chamber and 4-chamber view, and global peak systolic circumferential strain (GSC) and strain rate (GSrC) from papillary level short-axis view. Values were compared between the two groups. The correlations between EF and GSL, GSrL, GSC, GSrC were analyzed respectively. Results All parameters in heart failure patients were significantly lower than that in control subjects (P<0.001). There were good correlations between EF and GSL, GSrL, GSC, and GSrC (r=0.88, 0.87, 0.85 and 0.83, respectively). Conclusion Two-dimensional strain can quantify global LV strain and strain rate, and has the potential to be used clinically in accurate evaluation of LV function.
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