| 李尧,龚浠平,王拥军,李征.单侧颈动脉闭塞DSA的侧支血流分级与CT灌注的脑组织灌注分期之间的关系[J].中国医学影像技术,2006,22(6):845~849 |
| 单侧颈动脉闭塞DSA的侧支血流分级与CT灌注的脑组织灌注分期之间的关系 |
| Relations between collateral degrees by DSA and perfusion stages by CT perfusion in patients with unilateral carotid artery occlusion |
| 投稿时间：2006-02-10 修订日期：2006-04-28 |
| DOI： |
| 中文关键词: 颈动脉闭塞 侧支循环 数字减影血管造影 灌注 |
| 英文关键词:Carotid occlusion Collateral circulation Digital subtraction angiography Perfusion |
| 基金项目: |
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| 中文摘要: |
| 目的 研究单侧颈动脉闭塞同侧半球DSA的侧支血流分级与CT灌注的脑组织灌注分期之间的关系。方法 DSA证实的43例单侧颈动脉闭塞病人,将闭塞颈动脉同侧的大脑半球分为大脑中动脉皮层区域、前皮层分水岭区域、后皮层分水岭区域、内分水岭区域、穿支供血区域,对每个区域进行侧支血流分级和CT灌注分期,进行相关性分析。结果 侧支分级与组织灌注有很好的相关性(r＝-0.760, P<0.001),通过侧支分级≤1级判断非梗死区域脑血流量下降敏感性为79%,特异性为86%;通过组织灌注≤Ⅰ期来判断有完全的侧支血流敏感性97％,特异性73％。结论 DSA不仅提供侧支的形态学信息,也反映侧支的灌注信息,CT灌注能够反映侧支代偿情况,侧支分级与组织灌注有很好的对应关系。 |
| 英文摘要: |
| Objective To investigate the cerebral hypo-perfusion in pre-infarction period by CT perfusion imaging and cerebral infarction by CT and MRI ipsilateral to carotid artery occlusion, and the association between ischemic brain lesions and intracranial collateral blood flow in patients with unilateral carotid artery occlusion. Methods Forty-three patients with unilateral carotid artery occlusion confirmed by DSA were included. The degrees of collateral circulation and the stages of perfusion were evaluated in each of five cerebral anatomic regions ipsilateral to the occlusion. The five regions were territory cortical region of middle cerebral artery (MC), anterior watershed cortical region (AWS), posterior watershed cortical region (PWS), internal watershed region (IWS), and perforating artery region (PA). The relations between collateral degrees and perfusion stages in the same region were analyzed. Results Collateral grades correlated perfectly with perfusion stages in the same anatomic region (r＝-0.760, P<0.001). The sensitivity was 79% and the specificity was 86% for collateral grade ≤1 point to predict decreased cerebral blood flow in noninfarction regions. The sensitivity was 97% and the specificity was 73% for perfusion data ≤stage Ⅰ to predict complete collateral flow. Conclusion DSA provided angiographic information and perfusion data of collateral circulation, and CT perfusion imaging was associated with collateral flow. |
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