| 史瑞华,翟仁友,钱晓军,潘振宇,丁毅,鲁万红,孟昭泉,周意明,包娜,顾华.磁共振波谱成像在良恶性脑膜瘤鉴别诊断中的价值[J].中国医学影像技术,2006,22(5):674~677 |
| 磁共振波谱成像在良恶性脑膜瘤鉴别诊断中的价值 |
| Magnetic resonance spectroscopy in differential diagnosis of benign and malignant meningiomas |
| 投稿时间：2005-12-10 修订日期：2006-02-10 |
| DOI： |
| 中文关键词: 脑膜瘤 磁共振波谱 鉴别诊断 |
| 英文关键词:Meningiomas Magnetic resonance spectroscopy Differential diagnosis |
| 基金项目: |
| 作者 | 单位 | E-mail | | 史瑞华 | 首都医科大学附属北京朝阳医院放射科,北京 100020 | | | 翟仁友 | 首都医科大学附属北京朝阳医院放射科,北京 100020 | zhairenyou@vip.163.com | | 钱晓军 | 首都医科大学附属北京朝阳医院放射科,北京 100020 | | | 潘振宇 | 首都医科大学附属北京朝阳医院放射科,北京 100020 | | | 丁毅 | 首都医科大学附属北京朝阳医院放射科,北京 100020 | | | 鲁万红 | 首都医科大学附属北京朝阳医院放射科,北京 100020 | | | 孟昭泉 | 首都医科大学附属北京朝阳医院放射科,北京 100020 | | | 周意明 | 首都医科大学附属北京朝阳医院放射科,北京 100020 | | | 包娜 | 首都医科大学附属北京朝阳医院放射科,北京 100020 | | | 顾华 | 首都医科大学附属北京朝阳医院放射科,北京 100020 | |
|
| 摘要点击次数: 2604 |
| 全文下载次数: 1784 |
| 中文摘要: |
| 目的 探讨磁共振波谱(1H MRS)在良、恶性脑膜瘤鉴别诊断中的价值。方法 经手术病理证实的36例脑膜瘤在治疗前行常规MRI及1H MRS检查(脑膜瘤Ⅰ级30例,Ⅱ+Ⅲ级6例)。1H MRS检查包括PRESS 35 、PRESS 144序列。结果 良性脑膜瘤组Cho/Cr比值(3.80±1.08);恶性脑膜瘤组Cho/Cr比值(7.22±0.70)。差异具有显著性(t=7.40, P=0.000)。MRS表现:本组脑膜瘤病例均未测得NAA,可见Cho峰升高、Cr降低。35例可测得特异的Ala峰。36例均测得谷氨酸和谷胺酰胺(Glx)峰。5例恶性脑膜瘤于1.3 ppm 处见特异的Lip的亚甲基信号,而良性脑膜瘤中仅有1例纤维细胞型见Lip的亚甲基信号显示。 结论 脑膜瘤磁共振波谱Cho/Cr比值对脑膜瘤良、恶性鉴别诊断具有重要价值。1.3 ppm 处Lip的亚甲基信号多提示为恶性脑膜瘤可能。 |
| 英文摘要: |
| Objective To investigate the value of 1H magnetic resonance spectroscopy (1H MRS) in differentiating benign from malignant meningiomas. Methods Thirty-six patients with meningiomas underwent conventional MR and 1H MRS before surgery (GradeⅠ 30 cases; Grade Ⅱ+Ⅲ 6 cases). 1H MRS sequences included PRESS 35 and PRESS 144. Results The mean ratio of Cho/Cr in the benign and malignant groups were (3.80±1.08) and (7.22±0.70), respectively. The difference is significant (t=7.40, P=0.000). The MRS features of meningiomas were as follows: NAA cannot be detected. Cho increased markedly, Cr decreased evidently and Ala apex is very characteristic. Glx was observed in all cases. A methylene of Lip was detected in all five malignant meningiomas, but only in one benign meningioma (fibrous). Conclusion 1H MRS is an useful diagnostic method for differentiating benign from malignant meningiomas according to the Cho/Cr ratio. A methylene signal suggests a high grade tumor. |
| 查看全文 查看/发表评论 下载PDF阅读器 |
|
|
|
