| 张碧云,陈自谦,肖慧.中枢神经细胞瘤的影像学与临床病理分析[J].中国医学影像技术,2006,22(5):660~662 |
| 中枢神经细胞瘤的影像学与临床病理分析 |
| Imaging and clinicopathological analysis of central neurocytoma |
| 投稿时间：2005-11-23 修订日期：2006-01-24 |
| DOI： |
| 中文关键词: 中枢神经细胞瘤 体层摄影术,X线计算机 磁共振成像 病理学 |
| 英文关键词:Central neurocytoma Tomography, X-ray computed Magnetic resonance imaging Pathology |
| 基金项目: |
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| 摘要点击次数: 1986 |
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| 中文摘要: |
| 目的 探讨中枢神经细胞瘤(CNC)的影像学特点及临床病理表现。方法 回顾性分析经手术病理证实的CNC 5例,分析其影像学及临床病理表现。结果 本组病例中肿瘤均位于侧脑室透明隔,靠近Monro孔处,在CT上呈等或稍高密度,在MR T1WI呈等或稍低信号,T2WI上呈不均匀高信号,增强后可见不均匀明显强化。肿瘤均可见囊变,边缘清晰。免疫组化突触素(Syn)均为阳性表达,2例胶质纤维酸性蛋白(GFAP)阳性表达,1例S-100呈阳性表达,3例Ki-67阳性表达。结论 青年人位于透明隔的肿瘤,应考虑CNC的诊断,CT与MRI有助于诊断此病,确定手术方案。 |
| 英文摘要: |
| Objective To study the imaging features and clinicopathological findings of central neurocytoma. Methods Imaging and pathologic findings in 5 cases with pathologically-proved central neurocytoma were retrospectively analyzed. Results All tumors were located at the septum pellucidum between the lateral ventricles and close to Monro's foramen, presenting as iso-intensity or slightly hyperintensity on CT, iso-signal or slightly hypointense signal on MR T1WI, and mixed hyper-signal on T2WI. The lesion showed a marked inhomogeneous enhancement on CT and MRI. Cystic degenerations within the tumor were seen in most cases. The tumors showed a sharp border. In the result of immunohistochemical study, all 5 cases were positive for synptophysin (Syn), 2 cases were positive for glial fibrillary acid protein (GFAP), 1 case was positive for S-100, and 3 cases were positive for Ki-67. Conclusion Central neurocytoma should be considered when a mass located at septum pellucidum is found in a young patient. CT and MRI are helpful for making a preoperative diagnosis and surgical plan. |
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