白亮彩,郭顺林,周怀琪,雷军强,窦郁,张毅.1H MRS在定量分析脂肪肝中的初步研究[J].中国医学影像技术,2006,22(4):529~531
1H MRS在定量分析脂肪肝中的初步研究
1H MR spectroscopy in quantitative evaluation of fatty liver: pilot study
投稿时间:2005-11-05  修订日期:2005-11-29
DOI:
中文关键词:  磁共振波谱学  超声检查  脂肪肝
英文关键词:Magnetic resonance spectroscopy  Ultrasonography  Fatty liver
基金项目:
作者单位E-mail
白亮彩 兰州大学第一医院放射科,甘肃 兰州 730000 bailiangcai@126.com 
郭顺林 兰州大学第一医院放射科,甘肃 兰州 730000  
周怀琪 兰州大学第一医院放射科,甘肃 兰州 730000  
雷军强 兰州大学第一医院放射科,甘肃 兰州 730000  
窦郁 兰州大学第一医院放射科,甘肃 兰州 730000  
张毅 兰州大学第一医院放射科,甘肃 兰州 730000  
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中文摘要:
      目的 探讨1H磁共振波谱(1H MRS)定量检测脂肪肝的可行性。方法 对B超筛选出的20例健康志愿者及18例弥漫性脂肪肝患者分别行常规MR平扫、1H MRS成像,得到水和脂质波峰,利用GE Functool软件进行分析,测量各峰值与波峰下面积,与B超所得结果进行比较。结果 1例超声诊断为脂肪肝患者在波谱成像时未出现明显脂峰, 余1H MRS所得波谱曲线与B超声像图测量结果一致,正常组与病例组水峰无明显差异,而脂质峰有显著差异, 并且病例组内脂峰也有差异。结论 1H MRS可以对脂肪肝进行定量分析。
英文摘要:
      Objective To investigate the feasibility of quantitative detecting fatty liver by 1H MR spectroscopy (1H MRS) imaging. Methods Eighteen patients with diffuse fatty liver and 20 healthy volunteers screened out by ultrasonography underwent conventional MR scan, 1H MRS imaging, and H2O peak and lipid peak were acquired. The peak value was measured and the areas under the peaks were calculated by GE Functool software, and were compared with the results of ultrasonography. Results The results of 1H MRS were in accordance with the results of ultrasonography except in one case. H2O peak had no obvious difference between the two groups, but lipid peak had obvious difference between the two groups, also in cases of fatty liver. Conclusion 1H MRS imaging provides the possibility of quantitative detecting fatty liver.
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