张彦彬,朱家瑞,康静波,聂青,杨志祥.18F-FDG符合线路/CT显像在非小细胞肺癌立体定向放疗中的应用[J].中国医学影像技术,2006,22(3):455~457
18F-FDG符合线路/CT显像在非小细胞肺癌立体定向放疗中的应用
Application of 18F-FDG coincidence/CT imaging in stereotactic radiotherapy of non-small cell lung cancer
投稿时间:2005-10-08  修订日期:2006-01-13
DOI:
中文关键词:  肺肿瘤  18F-FDG 符合线路/CT显像  肿瘤分期  立体定向放疗
英文关键词:Lung neoplasm  18F-FDG coincidence/CT imaging  Tumor staging  Stereotactic radiotherapy
基金项目:
作者单位E-mail
张彦彬 军事医学科学院附属医院烧伤整形科,北京 100071  
朱家瑞 海军总医院核医学科,北京 100071 jiarui_zhu@csnm.com.cn 
康静波 海军总医院放射肿瘤科,北京 100037  
聂青 海军总医院放射肿瘤科,北京 100037  
杨志祥 军事医学科学院附属医院烧伤整形科,北京 100071  
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中文摘要:
      目的 探讨18F-脱氧葡萄糖符合线路/CT显像在非小细胞肺癌(NSCLC)立体定向放疗中的应用。方法 53例NSCLC患者于放射治疗前行18F-FDG显像检查,进行FDG分期,并将FDG分期和CT分期结果进行比较分析。结果 18F-FDG符合线路/CT显像使26例NSCLC患者分期改变,其中分期升级20例,分期降级6例。11例分期升级者PET检查发现了远处转移灶,其治疗方案由根治性治疗改为姑息性治疗;FDG显像较CT多发现39个转移淋巴结,并对其进行了立体定向放疗。FDG显像较CT多发现远处转移灶22个,对转移病灶进行了姑息性放疗。结论 18F-FDG符合线路/CT显像改变了49.06%(26/53)NSCLC患者的临床分期,影响了其治疗策略及放疗计划。
英文摘要:
      Objective To investigate the apply of 18F-FDG coincidence/CT imaging in the stereotactic radiotherapy of non-small cell lung cancer (NSCLC). Methods Fifty-three patients with NSCLC had been examined by 18F-FDG coincidence/CT and staged by FDG imaging before radiotherapy. The results of 18F-FDG coincidence/CT examination were compared with those of CT. Results The staging was changed in 26 patients because of 18F-FDG coincidence/CT findings, with 20 patients being upstaged and downstaged in 6 patients. Because of distant metastasis detected by FDG imaging, 11 patients received palliative treatment. Compared with CT, 39 more lymph nodes and 22 distant metastasis were found in FDG imaging, then received stereotactic radiotherapy and palliative treatment respectively. Conclusion 18F-FDG coincidence/CT imaging, by changing clinical staging in 49.06%(26/53) NSCLC patients, has impact on treatment strategy and treatment planning of stereotactic radiotherapy in NSCLC patients.
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