| 李宗芳,田伟,顾青,莫茵,包颜明,陈连有,徐江波.多体素氢质子波谱对脑脓肿的诊断价值[J].中国医学影像技术,2006,22(3):392~394 |
| 多体素氢质子波谱对脑脓肿的诊断价值 |
| Role of 1H MR spectroscopy in diagnosis of brain abscesses |
| 投稿时间：2005-09-05 修订日期：2005-12-01 |
| DOI： |
| 中文关键词: 脑脓肿 磁共振成像 波谱分析 |
| 英文关键词:Brain abscess Magnetic resonance imaging Spectrum analysis |
| 基金项目: |
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| 中文摘要: |
| 目的 探讨磁共振氢质子波谱(1H-MRS)技术对脑脓肿的诊断价值。方法 对9例脑脓肿病人行常规MRI和1H-MRS扫描。完成扫描后用随机分析软件包Functool 2进行分析,获得脓液和脓肿壁的波谱图。结果 9例病灶中8例检测到氨基酸(AA)峰,1例没有AA峰。另有2例脓液培养见厌氧菌生长的脓肿的波谱图中可见乙酸(Ac)峰和琥珀酸(Suc)峰。9例脓肿壁与对侧正常脑组织比较:Cho和NAA低于对侧并有显著性差异,Cho/NAA无显著性差异。结论 1H-MRS不但可提高细菌性脑脓肿的诊断准确率,而且还可根据Ac峰和Suc峰的有无提示是否厌氧菌感染,为临床治疗提供非常有价值的信息。 |
| 英文摘要: |
| Objective To investigate the value of 1H-MRS in the diagnosis of brain abscesses. Methods Conventional MR imaging and 1H-MRS data were obtained from 9 patients with brain abscess. Metabolite patterns of pus and wall of abscess were retrospectively analyzed by using Functool 2 software. Results AAs were observed in 8 of 9 patients. Ac and Suc were observed in 2 of 9 patients in which pus culture were positive for obligate aerobes. On 1H-MRS, Cho and NAA of abscess wall were significantly lower than that of normal control tissues (P<0.01), but Cho/NAA was not different significantly than that of normal control tissues (P>0.05). Conclusion 1H-MRS can not only improve the accuracy of diagnosis, but also differentiate anaerobic from aerobic or sterile brain abscess on the basis of metabolite patterns observed at 1H-MRS. It provides valuable information for appropriate patient management. |
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