任小龙 综述,周晓东 审校.HIFU技术中的超声空化及空化增强效应研究进展[J].中国医学影像技术,2006,22(2):310~312 |
HIFU技术中的超声空化及空化增强效应研究进展 |
Progress of ultrasonic cavitation and cavitation-induced enhancement effectin high intensity focused ultrasound |
投稿时间:2005-07-10 修订日期:2005-10-10 |
DOI: |
中文关键词: 高强度聚焦超声 造影剂,微泡 空化效应 图像增强 |
英文关键词:High intensity focused ultrasound Contrast media , microbubbles Cavitation Image enhancement |
基金项目:本课题为国家自然科学基金资助项目(30570489)。 |
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中文摘要: |
超声空化效应是高强度聚焦超声( HIFU) 治疗中的重要效应之一,有效诱导并且利用超声空化效应可以增加HIFU 辐照后的组织凝固范围和提高HIFU 疗效。微泡造影剂被确认为是提高HIFU 疗效的一种重要增效剂,其作用就是作为超声空化效应的空化核,降低聚焦超声对组织的损伤阈值从而可以扩大组织的凝固范围。随着对HIFU 增效作用的研究进展,HIFU 技术必将更加高效、安全,成为临床治疗肿瘤的有力武器。 |
英文摘要: |
Ult rasonic cavitation is one of predominant mechanisms in high intensity focused ultrasound ( HIFU) treatment .Efficiently-induced ult rasonic cavitation can be used to increase the coagulated volume and enhance the therapeutic efficiencyof HIFU. Recent studies have shown that microbubble cont rast agents are important factors in enhancing the therapeutic ef-ficiency of HIFU. They have potential to act as cavitation nuclei and are likely to lower the tissue damage threshold and causea greater coagulated volume. Along with the development of HIFU efficiency enhancement studies , HIFU will be more effec-tive and powerful in clinical tumor treatment . |
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