金修才,赵宝珍,李娟,姜红,章建全.同种异体肾移植患者肾功能变化与叶间动脉阻力指数和搏动指数变化的相关性分析[J].中国医学影像技术,2006,22(2):263~265
同种异体肾移植患者肾功能变化与叶间动脉阻力指数和搏动指数变化的相关性分析
Relation between renal function and resistance index and pulsatility indexof the interlobar artery in renal allograft recipients
投稿时间:2005-08-22  修订日期:2005-11-11
DOI:
中文关键词:  超声检查,多普勒,彩色  肾移植  阻力指数  搏动指数  肾功能
英文关键词:Ultrasonography , Doppler , color  Kidney transplantation  Resistance index  Pulsatility index  Renal func-tion
基金项目:
作者单位E-mail
金修才 上海长征医院超声科,上海200003 goldenxc@126.com 
赵宝珍 上海长海医院超声科,上海200433  
李娟 萍乡矿业集团总医院超声科,江西萍乡337042  
姜红 上海长征医院超声科,上海200003  
章建全 上海长征医院超声科,上海200003  
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中文摘要:
      目的 运用彩色多普勒超声测量移植肾叶间动脉的阻力指数(RI) 和搏动指数(PI) ,观察两者的变化情况与肾功能变化的关系。方法 在100 例无并发症肾移植患者中,应用彩色多普勒超声,于肾移植术后1 月测量移植肾叶间动脉的RI 和PI。测定患者血清肌酐、非蛋白氮及血白蛋白,根据MDRD 公式计算肾小球滤过率( GFR) 。随访2 年后再行一次上述超声和肾功能检查,比较叶间动脉RI、PI 和肾功能的变化情况,作RI、PI 变化值与GFR 变化值的相关性分析。结果 叶间动脉的RI 和PI 在随访前后与GFR 无明显的相关,随访前后RI 和PI 的改变与GFR 的改变呈明显的负相关。100 例患者中,21 例患者出现了肾功能异常,79 例的肾功能仍然正常。根据2 年后的肾功能有无异常将患者分为GFR 正常组和GFR 异常组。两组随访前后叶间动脉的RI 和PI 变化与GFR 变化呈明显的负相关。结论 多普勒彩超动态监测移植肾叶间动脉的RI 和PI 变化能够预测移植肾肾功能的变化。
英文摘要:
      Objective We measured resistance index (RI) and pulsatility index (PI) of interlobar artery to detect the rela-tionship of changes of allograf t function with changes of interlobar artery RI and PI in renal t ransplantation recipient s. Meth-ods RI and PI of interlobar artery in 100 noncomplicated renal transplantation recipient swere obtained by color Doppler ul-t rasonography at one month after transplantation. The serum creatinine , blood urea nitrogen and albumin were determined inorder to calculate the glomerular filt ration rate ( GFR) according to formula. Af ter 2 years’ follow up , the above measure-ment s were performed again. The correlation of changes of GFR and changes of interlobar artery RI and PI was analyzed.Results There was no significant correlation between RI , PI and GFR , and there was a significant negative relationship be-tween changes of RI , PI and changes of GFR in all the subject s. Af ter 2 years’ follow up , GFR of 79 patient s was still nor-mal , and the other 21 patient s showed decreased GFR. Patient s were divided into normal GFR group and abnormal GFRgroup according to the GFR after follow up. There was a significant negative relationship between changes of RI , PI andchanges of GFR in two group s. Conclusion The changes of RI and PI of interlobar artery measured by Doppler ult rasonog-raphy can be used to predict the changes of GFR in noncomplicated renal transplantation.
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