李锐,郭燕丽,何芸,张晓航,丁俊,陈朝晖.脉冲反向谐波实时超声造影对肝占位病变良恶性的鉴别诊断[J].中国医学影像技术,2006,22(2):186~188
脉冲反向谐波实时超声造影对肝占位病变良恶性的鉴别诊断
Real-time pulse-inversion sonography using contrast agent :differentiation between benign and malignant focal liver lesions
投稿时间:2005-08-07  修订日期:2005-11-04
DOI:
中文关键词:  超声检查  肝肿瘤  造影剂
英文关键词:Ult rasonography  Liver neoplasms  Cont rast media
基金项目:
作者单位E-mail
李锐 第三军医大学西南医院超声科,重庆400038 raylee_7991@yahoo.com.cn 
郭燕丽 第三军医大学西南医院超声科,重庆400038  
何芸 第三军医大学西南医院超声科,重庆400038  
张晓航 第三军医大学西南医院超声科,重庆400038  
丁俊 第三军医大学西南医院超声科,重庆400038  
陈朝晖 第三军医大学西南医院超声科,重庆400038  
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中文摘要:
      目的 探讨低机械指数实时超声造影鉴别肝占位病变良恶性的临床应用价值。方法 采用静脉团注造影剂SonoVue 和低机械指数脉冲反向谐波技术对192 例肝占位病变(109 例恶性肿瘤,83 例良性病变) 进行实时灰阶超声造影,将造影前后病灶评分与病理结果进行比较分析。结果 超声造影前肝脏恶性肿瘤诊断的敏感性、特异性和准确性分别为52. 3 %、44. 6. %和49. 0 % ,造影后分别提高到89. 0 %、96. 4 %和92. 2 %(P < 0. 01) 。结论 低机械指数实时超声造影可明显增强对肝占位病变良恶性的鉴别诊断能力。
英文摘要:
      Objective To assess the ability of low mechanical index real-time pulse-inversion sonography in revealing differ-ences between benign and malignant focal hepatic lesions. Methods One hundred and ninety-two patient s with focal hepaticlesions (109 malignant lesions and 83 benign lesions) detected by B-mode sonography were examined by using low mechanicalindex real-time pulse-inversion sonography af ter cont rast agent SonoVue injection. The rating scores (52point system) , sen-sitivity , specificity and accuracy were calculated by considering histological analysis. Results Cont rast agent SonoVue en-hanced real-time sonography improved the sensitivity from 52. 3 % to 89. 0 % , the specificity from 44. 6 % to 96. 4 % and theaccuracy f rom 49. 0 % to 92. 2 % compared with baseline sonograpy ( P < 0. 01) . Conclusion Low mechanical index real2timepulse2inversion sonography led to improving the differentiation of benign and malignant liver lesions significantly.
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