| 董鹏,王滨,孙西河,常光辉,李绪斌,陈静静.肺癌脑转移瘤瘤周水肿程度的影响因素研究[J].中国医学影像技术,2006,22(1):57~59 |
| 肺癌脑转移瘤瘤周水肿程度的影响因素研究 |
| Factors of the edema-size of intracranial metastases from lung cancer |
| 投稿时间：2005-09-05 修订日期：2005-11-06 |
| DOI： |
| 中文关键词: 脑转移瘤 肺肿瘤 磁共振成像 多因素分析 |
| 英文关键词:Int racranial metastases Lung neoplasms Magnetic resonance imaging Multiple factor analysis |
| 基金项目: |
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| 摘要点击次数: 2548 |
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| 中文摘要: |
| 目的 研究影响肺癌脑转移瘤瘤周水肿程度的因素。方法 回顾性分析经手术病理和/ 或临床证实的肺癌脑转移瘤MRI 资料26 例(男13 例,女13 例,年龄34～75 岁,平均57.71 岁) ,所有患者均进行增强扫描。从断层像上观察瘤灶在脑内的分布情况,分别观察记录:瘤周水肿的大小、瘤灶的大小、瘤灶中心到最近灰质边缘的距离、瘤灶的强化特点(均匀强化、不均匀强化和环状强化) 、瘤灶在脑内分布(大脑半球、小脑和脑干) 的情况等,同时记录瘤灶的组织学类型(小细胞肺癌和非小细胞肺癌) 、患者的年龄和性别。以瘤灶瘤周水肿的大小为应变量,以性别、年龄、组织学类型、瘤灶大小、瘤灶中心到最近灰质边缘的距离、瘤灶的强化类型、瘤灶的部位为自变量,进行多因素相关性分析。结果①26 例肺癌脑转移瘤病人中,肺癌组织学类型为小细胞肺癌8 例,非小细胞肺癌18 例,共包括92 个瘤灶。92个瘤灶中,瘤周水肿的大小为0～5.1cm ,瘤灶大小为0.2～5.0cm ,瘤灶中心到最近灰质边缘的距离为0.1～2.5 cm ,均匀强化、不均匀强化和环状强化分别为40个、13个和39个,大脑半球、小脑和脑干分别为72个、17个和3个。②瘤灶瘤周水肿程度与瘤灶大小、与灰质边缘的距离及部位有相关性,且与瘤灶大小、与灰质边缘的距离成正相关,与部位成负相关(F= 20.04 ,P<0.0001)。结论 肺癌脑转移瘤瘤周水肿程度与瘤灶大小、瘤灶中心到最近灰质边缘的距离和瘤灶分布部位有关,与瘤灶的强化类型、组织学类型、性别和年龄无关。 |
| 英文摘要: |
| Objective To study the influential factors of the edema2size of the int racranial metastases f rom lung cancer.Methods Twenty2six patient s (13 male and 13 female , mean age 55. 71 years , range f rom 34 to 75 years,) with pathologi-cally/ clinically proved int racranial metastases f rom lung cancer were reviewed ret rospectively. All cases underwent plain andcont rast2enhanced scanning , emphases were focused on the followings:the diameter of metastases , the distance f rom thetumor center to the nearest cortex wall, enhanced features, the sex, age and histological type. The above 7 variables wereinvestigated by multiple factor analysis.Results ①Among 26 cases, 8 cases were small cell lung cancer, 18 cases were non-small cell lung cancer. Ninety-two metastases were found in 26 cases , edema-size ranged 0-5.1cm; the diameter of metas-tases ranged 0.2-5.0cm; the distance f rom the tumor center to the nearest cortex wall ranged 0.1-2.5cm. Forty metas-tases were homogeneous enhanced, 13 metastases were heterogeneous enhanced, 39 metastases were ring-like enhanced. ②Multiple factor analysis indicated that the influential factors of the edema2size of the metastases were the diameter of metasta-ses , the distance fromtumor center to nearest cortex wall, and the site of the metastases (F=20.04 ,P<0.0001). Conclu-sion The diameter of metastases, the distance f rom the tumor center to the nearest cortex wall, and the site of the metasta-ses were the influential factors of the edema-size of the int racranial metastases f rom lung cancer. |
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