| 姜露莹,张贵祥,杨亚汝,张峰.兔VX2肾癌模型的制作方法改进及超声观察[J].中国医学影像技术,2006,22(1):45~47 |
| 兔VX2肾癌模型的制作方法改进及超声观察 |
| Improvement of building rabbit renal VX2 tumor models and ultrasonographic observation |
| 投稿时间：2005-06-10 修订日期：2005-08-26 |
| DOI： |
| 中文关键词: VX2 肾肿瘤 超声检查 兔 |
| 英文关键词:VX2 Renal neoplasms Ultrasonography Rabbits |
| 基金项目: |
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| 中文摘要: |
| 目的 探讨兔肾癌模型的制作方法及超声在肾癌生长中的监测作用。方法 新西兰大白兔30 只平均分为两组,A 组采用超声引导下组织块注射法,B 组采用手术直视下组织块接种法建立VX2 肾癌模型,比较两种方法的成瘤率,种植后隔天一次监测VX2 肾癌的超声声像变化。结果 超声引导组和手术组的种植成功率分别为53.3 %(8/ 15) 和86.7 %(13/ 15) ,超声引导组的肾包膜下血肿和肾外种植率均高于术中组;VX2 小肾癌的超声声像特征与临床小肾癌接近。结论 手术直视下组织块注射法是建立VX2 肾癌模型的可靠方法,成功率高。超声是监测兔VX2 肾癌生长的简便可靠的影像学方法之一。 |
| 英文摘要: |
| Objective To discuss the method of building rabbit renal tumor models and investigate the value of ult rasonog-raphy in observing the tumors growth. Methods Thirty New Zealand white rabbit s were randomly divided into two groups ,15 in each group. In group A, VX2 tumor tissue was inoculated into the rabbit kidney percutaneously under ult rasound guid-ance. In group B , VX2 tumor tissue was inoculated directly into the exposed kidney by surgery. The ult rasonographic fea-tures of renal tumors were recorded every other day af ter inoculation. Results The inoculated success rate of group A was53.3 %(8/ 15),while that of group Bwas 86.7 %(13/15).The incidence of subcapsular haematoma and peri-renal inocula-tion of ult rasound-guided group was higher.The ult rasonographic features of small rabbit VX2 renal tumor were similar withthat of renal tumor in human. Conclusion The model of rabbit renal tumor was successfully established by direct inoculationwith VX2 tumor tissue. Ultrasonography is auseful imaging technique in observing the tumor growth in the rabbit . |
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