| 高歌军,冯晓源,李克,耿道影,汤伟军,徐文东,顾玉东.初级运动皮层躯体分布图功能磁共振成像研究[J].中国医学影像技术,2006,22(1):7~10 |
| 初级运动皮层躯体分布图功能磁共振成像研究 |
| Somatotopic mapping of the human primary motor cortexmeasured with functional MRI |
| 投稿时间：2005-06-12 修订日期：2005-08-25 |
| DOI： |
| 中文关键词: 磁共振成像,功能性 脑 皮层 躯体分布 |
| 英文关键词:Magnetic resonance imaging, functional Brain Cortex Somatotopy |
| 基金项目:本研究受国家自然基金资助(30270402,30200288). |
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| 中文摘要: |
| 目的 检验功能性磁共振绘制大脑初级运动皮层躯体分布的能力和激活区特点。方法 12 例健康志愿者完成手部、肘部和肩部简单上肢运动任务。功能磁共振检查采用平面回波BOLD 序列,得出原始图像,利用SPM 99 软件进行图像后处理,记录初级运动皮层最强信号像素Talairach 坐标值,然后采用方差分析方法对x、y、z 轴数值进行统计分析。结果 所有受检者上肢各部分运动均可以在对侧初级运动皮层产生具有统计学意义的信号变化。激活区分布遵循躯体分布模式,统计分析显示:手部、肘部和肩部激活区最强信号像素x 轴数值存在显著差异,手部和肩部激活区最大信号像素z 轴数值也存在显著差异。结论 fMRI 能够准确绘制个体初级运动皮层躯体分布图。 |
| 英文摘要: |
| Objective To test the capability of functional magnetic resonance imaging (fMRI) in mapping the somatotopic organization in the primary motor cortex. Methods Self2paced repetitive simple movements of the upper ext remity were per-formed by 12 healthy volunteers. The raw data were acquired by using echo2planer BOLD sequence. Then , the SPM 99 sof t-ware was used for post rocessing. The position of the most significant voxel of active area of the Talairach coordinates in the primary motor cortex was recorded and the statistic analysis of variance was used for X , Yand Z value. Results Statistically significant MR signal changes were observed within cont ralateral primary motor cortex in all subject s and movement condi-tions. The pattern of functional activity followed a topographic representation. Statistic analysis indicated that there was sig-nificant difference among hand, elbow and shoulder movement in X value. The Z value between hand and shoulder alsoshowed significant difference. Conclusion These findings indicate that fMRI is capable of generating somatotopic maps in the primary motor cortex in individual subjects. |
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