张春燕,王霄英,李飞宇,许玉峰,蒋学祥.磁共振扩散加权成像对前列腺癌患者盆腔淋巴结诊断价值的初步研究[J].中国医学影像技术,2005,21(12):1862~1865
磁共振扩散加权成像对前列腺癌患者盆腔淋巴结诊断价值的初步研究
Assessment of diffusion-weighted MR imaging for pelvic lymph node in patients with prostate cancer: a preliminary study
投稿时间:2005-09-14  修订日期:2005-11-29
DOI:
中文关键词:  扩散加权成像  前列腺肿瘤  良性前列腺增生  淋巴结  磁共振成像
英文关键词:Diffusion-weighted imaging  Prostate neoplasms  Benign prostate hyperplasia  Lymph node  Magnetic resonance imaging
基金项目:
作者单位E-mail
张春燕 北京大学第一医院医学影像科,北京 100034  
王霄英 北京大学第一医院医学影像科,北京 100034 bjwxycn@tom.com 
李飞宇 北京大学第一医院医学影像科,北京 100034  
许玉峰 北京大学第一医院医学影像科,北京 100034  
蒋学祥 北京大学第一医院医学影像科,北京 100034  
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中文摘要:
      目的 初步评价扩散加权成像(DWI)对前列腺癌及良性前列腺增生患者淋巴结的鉴别诊断价值。方法 回顾性分析15例前列腺癌患者(58个淋巴结)及15例良性前列腺增生患者(30个淋巴结)的DWI表现(b=300 s/mm2),分别测量这些淋巴结的表观扩散系数(ADC),将癌与增生患者的淋巴结ADC值进行比较。结果 良性前列腺增生患者淋巴结的平均ADC值 明显大于前列腺癌患者 (P=0.000)。前列腺癌患者短径<1.0 cm的淋巴结 与≥1.0 cm淋巴结的ADC值 无显著性统计学差异(P=0.459)。前列腺患者短径<1.0 cm的淋巴结ADC值 小于前列腺增生患者淋巴结的ADC值 (P=0.003)。前列腺癌患者短径/长径<0.7的淋巴结ADC值 要高(P=0.039)。结论 DWI有可能用于前列腺癌淋巴结转移的检出。
英文摘要:
      Objective To assess the diagnostic value of diffusion-weighted imaging (DWI) for lymph node in patients with prostate cancer from that of benign prostate hyperplasia. Methods The diffusion-weighted images (b=300 s/mm2) of 15 patients with prostate cancer (58 lymph nodes) and 15 patients with benign prostate hyperplasia (30 lymph nodes) were retrospectively analyzed, with apparent diffusion coefficient (ADC) of all the lymph nodes measured and the ADC between patients of cancer and hyperplasia compared. Results The ADC of lymph nodes was significantly greater in patients with benign prostate hyperplasia than that with prostate cancer (P=0.000). The ADC between lymph nodes with short axis smaller than 1.0 cm and that with short axis greater than 1.0 cm in patients of prostate cancer showed no statistical significance (P=0.459). The ADC of lymph nodes with short axis smaller than 1.0 cm in patients with prostate cancer was smaller than that in patients with prostate hyperplasia [(2.282±0.573)×10-3 mm2/s)(P=0.003). The ADC of lymph nodes with ratio of short axis to long axis smaller than 0.7 [(1.631±0.205)×10-3 mm2/s) was higher than that of the ratio greater than 0.7 [(1.594±0.283)×10-3 mm2/s) in patients of prostate cancer (P=0.039). Conclusion DWI may be useful in discriminating metastatic lymph nodes of patients with prostate cancer.
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