| 杨莉,伍卫,王景峰,张小玲.脉冲组织多普勒对冠心病患者左室局部舒张功能变化的研究[J].中国医学影像技术,2005,21(11):1701~1703 |
| 脉冲组织多普勒对冠心病患者左室局部舒张功能变化的研究 |
| Assessment of regional left ventricular diastolic dysfunction in patientswith coronary artery disease by pulsed tissue Doppler imaging |
| 投稿时间：2005-07-23 修订日期：2005-08-20 |
| DOI： |
| 中文关键词: 组织多普勒成像 超声心动描记术 冠心病 心室功能,左 |
| 英文关键词:Tissue Doppler imaging Echocardiography Coronary artery disease Ventricular function, left |
| 基金项目: |
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| 中文摘要: |
| 目的 应用脉冲组织多普勒成像(TDI)定量分析并比较心绞痛与心肌梗死(心梗)患者左室壁不同节段心肌长轴方向舒张运动速度和时相变化,评价TDI速度和时间参数检测左室局部舒张功能异常的价值。方法 冠心病心绞痛组16例、前壁心梗组21例,对照组16例。记录左室侧壁、间隔、前壁和下壁基底段及中段心肌运动频谱。检测指标:心肌舒张早期峰值速度(e)、心肌舒张晚期峰值速度(a)、e/a比值、e波开始时间(QE)、e波峰值时间(Te)和局部等容舒张时间(IVRT)。结果 冠心病两 |
| 英文摘要: |
| Objective To quantitatively analyze and compare the longitudinal myocardial diastolic velocity and time intervals of the left ventricle in patients with angina pectoris (AP) with those in patients with myocardial infarction (MI), and to explore the value of diastolic velocity and time intervals measured by pulsed tissue Doppler imaging (TDI) in detecting regional left ventricular diastolic dysfunction. Methods Patients with coronary artery disease (CAD) were divided into AP group (16 cases) and anterior wall MI group (ant-MI, 21 cases). Sixteen age-matched normal subjects served as a control group. The septum and lateral, anterior and inferior wall of the left ventricle were displayed respectively, and basal and middle segments of each wall were selected for myocardial motion spectrum sampling. TDI parameters were: peak early diastolic velocity (e), peak late diastolic velocity (a),e/a ratio, time to the beginning of e wave (QE),time to the peak of e wave (Te),regional isovolumic relaxation time (IVRT). Results Compared with the control group, e and e/a were significantly lower in all segments in AP group and ant- MI group. The a and e were lower, but e/a was higher in infarct segments than corresponding non-infarct segments in ant-MI group. The QE, Te and IVRT were significantly longer in both AP group and ant-wall-MI group. However, only IVRT was longer in ant-wall-MI group than in AP group. Conclusion The e, e/a, QE, Te and IVRT measured by TDI are all sensitive markers of regional left ventricular diastolic dysfunction in patients with CAD, and IVRT may also respond to the severity of myocardial ischemia. |
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