熊润青,谢明星,王新房,吕清,王静,卢晓芳,杨亚利,贺林,龙莎,张静,龚静吉.超声应变显像技术评价肥厚性心肌病局部心肌功能的探讨[J].中国医学影像技术,2005,21(11):1697~1700
超声应变显像技术评价肥厚性心肌病局部心肌功能的探讨
Assessment of regional myocardial function in patients with hypertrophic cardiomyopathy by tissue strain imaging
投稿时间:2005-07-22  修订日期:2005-09-12
DOI:
中文关键词:  超声心动描记术  应变显像  心肌病,肥厚性  局部心肌功能
英文关键词:Echocardiography  Strain imaging  Cardiomyopathy, hypertrophic  Regional myocardial function
基金项目:
作者单位E-mail
熊润青 华中科技大学同济医学院附属协和医院超声影像科,湖北 武汉 430022  
谢明星 华中科技大学同济医学院附属协和医院超声影像科,湖北 武汉 430022 xmxxyj@public.wh.hb.cn 
王新房 华中科技大学同济医学院附属协和医院超声影像科,湖北 武汉 430022  
吕清 华中科技大学同济医学院附属协和医院超声影像科,湖北 武汉 430022  
王静 华中科技大学同济医学院附属协和医院超声影像科,湖北 武汉 430022  
卢晓芳 华中科技大学同济医学院附属协和医院超声影像科,湖北 武汉 430022  
杨亚利 华中科技大学同济医学院附属协和医院超声影像科,湖北 武汉 430022  
贺林 华中科技大学同济医学院附属协和医院超声影像科,湖北 武汉 430022  
龙莎 华中科技大学同济医学院附属协和医院超声影像科,湖北 武汉 430022  
张静 华中科技大学同济医学院附属协和医院超声影像科,湖北 武汉 430022  
龚静吉 华中科技大学同济医学院附属协和医院超声影像科,湖北 武汉 430022  
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中文摘要:
      目的 探讨超声组织应变显像(SI)技术评估肥厚性心肌病(HCM)患者局部心肌收缩与舒张功能的价值。方法 HCM患者30例,25例正常人为对照组。选取标准的心尖四腔切面,在心动周期中分别测量室间隔与左室侧壁基底段、中间段、心尖段沿心脏长轴方向上的收缩期峰值应变(εet),观察HCM组出现的收缩期反向应变节段;统计两组室间隔中段和后壁中段的收缩后应变(PSS)节段数并计算其幅度值;将室间隔中段的应变值与室壁厚度进行相关分析。结果 ①正常组各节段ε
英文摘要:
      Objective To assess regional myocardial systolic and diastolic function in patients with hypertrophic cardiomyopathy (HCM) by tissue strain imaging (SI). Methods Doppler echocardiography and SI were performed in patients with HCM (n=30) and age-matched healthy subjects (n=25) at apical four-chamber view. Regional longitudinal peak systolic strain was measured at basal, mid and apical segments of septal and lateral walls in both groups, compared between both groups and between intragroup, reversed segments were observed in HCM group. Meantime, post-systolic strain (PSS) segment numbers were counted and its amplitude was calculated; Correlation was analyzed between peak systolic strain and thickness in mid-septum. Results Peak systolic strain of different segment in patients with HCM was significant reduced than those in control group (P<0.05), peak systolic strain in the mid-septum was lowest and reversed segments were found in 40% thickening segment in the HCM group; PSS presents in both HCM and control groups, but amplitude of PSS in control group was less (P<0.05); There was a significant correlation between peak systolic strain and thickness in mid-septum (r=0.83). Conclusion Left ventricular regional myocardial systolic and diastolic function has been impaired in patients with HCM, especially in thickening segments. SI is a sensitive and accurate technology to detect it.
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