| 吕中伟,管梁,蔡海东,侯敏,余飞,郭万华,朱承谟.平面配对显像对99Tcm-C50，67Ga的内照射辐射吸收剂量分析[J].中国医学影像技术,2005,21(10):1592~1594 |
| 平面配对显像对99Tcm-C50，67Ga的内照射辐射吸收剂量分析 |
| Calculation of irradiated absorbed dosage in 99Tcm-C50, 67Ga by paired planar imaging |
| 投稿时间：2005-05-20 修订日期：2005-08-10 |
| DOI： |
| 中文关键词: 平面配对显像 99Tcm-C50 67Ga 辐射吸收剂量 |
| 英文关键词:Paired planar imaging 99Tcm-C50 67Ga Radiation absorbed dose |
| 基金项目:本课题受国家自然科学基金(39770236)和上海市科学技术发展基金(024119102)资助。 |
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| 中文摘要: |
| 目的 分析99Tcm-C50和67Ga 在病理状态下对各主要器官和全身的内照射剂量。方法 应用SPECT进行平面配对显像,以自行设计软件计算99Tcm-C50和67Ga 在直肠癌和淋巴瘤病人各组织器官的辐射吸收剂量。结果 发现99Tcm-C50主要累积在肝、肾中,肝、肾、肺和心的辐射吸收剂量较高; 67Ga主要累积在肠道、肝脏、肾脏和骨骼内,肠、肝、骨骼、肾脏和心脏内辐射吸收剂量较高。结论 本研究与ICRP第53号出版物公布的结论相近,且检测及计算方法简单、可靠,为临床合理应用上述两种放射性药物提供了实验性依据。 |
| 英文摘要: |
| Objective To analyze the radiation dose from internal exposure to individual organs and the whole body under pathological conditions. Methods Following paired planar imaging with SPECT, radiation absorbed doses of 99Tcm-C50 and 67Ga to individual organs or tissues were calculated using self-designed software in patients with rectal cancer or lymphoma. Results 99Tcm-C50 was accumulated mainly in liver and kidney. The high radiation absorbed doses were found in the liver, kidney, lung and heart. 67Ga was accumulated mainly in the intestines, liver, kidney and skeletons. The high radiation absorbed doses were found in the skeletons, intestines, liver, kidney and heart. Conclusion These Results are close to those published in No 53 of ICRP. The measurement and calculation provide a simple and relatively reliable way and experimental evidence for those two radiopharmaceuticals in clinical practice. |
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