| 张帅,彭卫军,唐峰,毛健,钱敏,师英强.脂肪对比剂灌肠MR结肠成像在结直肠肿瘤中的应用[J].中国医学影像技术,2005,21(10):1537~1539 |
| 脂肪对比剂灌肠MR结肠成像在结直肠肿瘤中的应用 |
| MR virtual colonography with fat contrast medium enema in detection of colorectal neoplasms |
| 投稿时间：2005-05-03 修订日期：2005-07-01 |
| DOI： |
| 中文关键词: 对比剂 磁共振成像 结肠成像 结直肠肿瘤 |
| 英文关键词:Contrast medium Magnetic resonance imaging Virtual colonography Colonic neoplasms |
| 基金项目:本研究受上海市科委和上海市卫生局科研发展基金资助(34958038)。 |
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| 中文摘要: |
| 目的 评估脂肪对比剂灌肠MR结肠成像检出结直肠肿瘤的可行性。方法 26例患者常规肠道准备和肌注山莨菪碱后,经直肠导管注入脂肪对比剂,采用3D FSPGR with IR (LAVA)序列加脂肪抑制,行MR增强前后冠状位扫描,一次屏气(28 s)包括全部结直肠。观察MR结肠成像质量和患者对脂肪对比剂的耐受性,并与结肠镜和病理进行对照,计算病变检出的敏感性。结果 所有患者均完成MR结肠成像检查。原始冠状位,多平面重建及MR仿真内镜成像质量良好。共有198个(95.2%)肠段扩张佳,增强后结直肠肿瘤的平均对比噪声比为16.2。大于10 mm病变的敏感性是95.8%。结论 脂肪对比剂灌肠MR结肠成像是能够检出结直肠肿瘤的有前景的方法,并且能评估结直肠腔外的腹部器官。 |
| 英文摘要: |
| Objective To evaluate the potential value of MR virtual colonography (MRVC) with fat contrast medium enema in the detection of colorectal neoplasms. Methods Twenty-six patients underwent MR colonography, after bowel preparation, administration of anisodamine and rectal administration of fat contrast medium. All patients were imaged with T1-weighted three-dimensional fast spoiled gradient-echo with inversion recovery (liver acquisition volume acceleration, LAVA) sequence under fat-saturation in the supine position before and after enhancement. Entire colon was covered in one contiguous coronal breath-hold acquisition lasting for 28 seconds or less. Two radiologists reviewed patient's tolerance, image quality, and sensitivity of colorectal neoplasms. The colorectal neoplasms detected with MRVC were compared with those identified on endoscopic and pathologic results. Results All patients completed the MR examination, including MR virtual endoscopy. Image quality (coronal imaging, multiplanar reformation and MR virtual endoscopy images) was good in all cases. 198/208 (95.2%) colonic segments were well distended in supine position. Mean contrast-to-noise ratio of colorectal masses was 16.2 for the post contrast scans. Sensitivity of lesions larger than 10 mm was 95.8%. Conclusion MRVC with fat contrast medium enema and LAVA sequence is a promising alternative method for detection of colorectal neoplasms. In addition, it allows assessment of extraluminal organs. |
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