朱庆莉,姜玉新,邓成艳.多胎妊娠超声引导生理盐水胚胎心腔部位注射减胎[J].中国医学影像技术,2005,21(10):1546~1548
多胎妊娠超声引导生理盐水胚胎心腔部位注射减胎
Injection of sodium chloride solution into the heart or nearby region of fetus under ultrasound guidance in cases of multifetal pregnancy reduction
投稿时间:2005-07-18  修订日期:2005-08-25
DOI:
中文关键词:  超声引导  多胎妊娠减胎术
英文关键词:Ultrasound-guided  Multifetal pregnancy reduction
基金项目:
作者单位E-mail
朱庆莉 中国医学科学院 中国协和医科大学 北京协和医院超声科, 北京 100730 qinglizhu@tom.com 
姜玉新 中国医学科学院 中国协和医科大学 北京协和医院超声科, 北京 100730 jiangyx@pumch.ac.cn 
邓成艳 中国医学科学院 中国协和医科大学 北京协和医院妇产科, 北京 100730  
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中文摘要:
      目的 探讨超声引导下多胎妊娠减胎术的改进方法。方法 多胎妊娠要求减胎的孕妇6例(孕8~13周)。术前超声检查确定减灭对象。3例采用经腹途径,3例采用经阴道途径。超声引导下直接穿刺胚胎心血管搏动处,快速注入2~3 ml生理盐水,超声监视下可见胚胎膨胀、正常形态消失,心搏停止,彩色多普勒血流信号消失。抽出等量羊水,观察保留胚胎的胎心搏动良好,减胎术完成。结果 6例患者均一次减胎成功,5例为3胎减至2胎,1例为5胎减至2胎。孕妇减胎术后均无子宫收缩,无阴道出血或流水。减胎后,妊娠期间活胎继续生长,1例于孕37周分娩,另5例尚在妊娠中。结论 超声引导下胚胎心腔部位生理盐水快速注射减胎术操作简便,机械性创伤小,使手术时间更短,成功率更高,并发症少,最大程度地保持存活胚胎的微环境稳定,具有重要的临床价值。
英文摘要:
      Objective To improve the procedures of ultrasound-guided multifetal pregnancy reduction. Methods Six consecutive cases of multifetal pregnancy reduction (MFPR) were included in this study. The gestational age was between 8 and 13 weeks. Transabdominal or transvaginal needle insertion under continuous ultrasound monitoring was used. Fetal reduction was achieved by the injection of sodium chloride into the fetal heart. An equal amount of the amniotic fluid was aspirated before the needle was removed. Data on pregnancy outcome were collected. Results The processes were successfully performed in all 6 cases by a single needle insertion. All cases were reduced to twins, 5 of the cases started with three fetuses, and 1 with five fetuses. No pregnancy loss observed in the series. Conclusion This study confirm that the injection of sodium chloride instead of high level of potassium chloride into the fetal heart is a safe and highly efficient procedure that leads to a better fetal and maternal outcome.
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