| 马娜,任卫东,杨欣,杨军,李玉宏,马春燕,李楠.声学造影评价动脉内-中膜厚度价值的实验研究[J].中国医学影像技术,2005,21(10):1484~1486 |
| 声学造影评价动脉内-中膜厚度价值的实验研究 |
| Effect of enhanced ultrasonography on measurement of arterial intimal-medial thickness: experimental study |
| 投稿时间：2005-06-18 修订日期：2005-09-12 |
| DOI： |
| 中文关键词: 声学造影 内-中膜厚度 兔 |
| 英文关键词:Enhanced ultrasonography Intima-media thickness Rabbit |
| 基金项目: |
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| 中文摘要: |
| 目的 探讨声学造影提高动脉内-中膜厚度(IMT)测量准确性的价值。方法 通过高脂饮食建立兔早期动脉粥样硬化模型,应用自制氟碳白蛋白声学造影剂,对造影前后颈总动脉内膜进行视觉分析及对比IMT差异,并行病理学检查。结果 造影后动脉各壁内膜回声明显增强,动脉前壁内膜识别较造影前显著改善。IMT不规则增厚,造影前常规超声测量前壁IMT(0.37±0.05) mm,较造影后测值(0.43±0.04) mm低估近14%,差异有显著性意义,与病理结果一致,动脉后壁造影前后IMT无显著差异。结论 声学造影可提高内膜分辨率及IMT测量准确性,对评价早期动脉病变有重要价值。 |
| 英文摘要: |
| Objective To explore the value of enhanced ultrasonography in measuring artery intima-media thickness (IMT). Methods Early rabbits atherosclerotic model were established by high cholesterol diet, contrast-enhanced common carotid artery was performed using self- made contrast agents, artery intima visibility and IMT difference with and without contrast agents were analyzed and compared with pathology. Results Significant increase of intima visibility was observed using contrast agents, especially for the anterior wall. IMT became irregularly thicker, measurement using standard ultrasound (0.37±0.05) mm underestimated the anterior wall IMT by 14% as compared to the contrast method (0.43±0.04) mm and histological results, while there was no difference in the posterior wall IMT. Conclusion Enhanced ultrasonography can improve intima visibility and accuracy of IMT measurement, thus play an important role in detecting early artery disease. |
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