| 方继良,金真,王寅,李科,曾亚伟,佟海滨,任燕双,高波,王映辉,程谟库.针刺太冲及其临近穴脑反应区功能磁共振成像比较[J].中国医学影像技术,2005,21(9):1332~1336 |
| 针刺太冲及其临近穴脑反应区功能磁共振成像比较 |
| Comparison of central effects of acupuncturing Taichongand nearby two acupoints by functional MRI |
| 投稿时间：2005-06-23 修订日期：2005-07-23 |
| DOI： |
| 中文关键词: 穴位相对特异性 磁共振成像,功能性 脑 |
| 英文关键词:Acupoint's specificity Magnetic resonance imaging , functional Brain |
| 基金项目:本研究受国家中医药管理局留学人员择优课题资助(国中医药2003L HR5) 。 |
| 作者 | 单位 | E-mail | | 方继良 | 中国中医研究院广安门医院放射科,北京 100053 | fangjiliang@sohu.com | | 金真 | 解放军306 医院放射科,北京 100083 | | | 王寅 | 中国中医研究院广安门医院针灸科,北京 100053 | | | 李科 | 解放军306 医院放射科,北京 100083 | | | 曾亚伟 | 解放军306 医院放射科,北京 100083 | | | 佟海滨 | 中国中医研究院广安门医院放射科,北京 100053 | | | 任燕双 | 中国中医研究院广安门医院放射科,北京 100053 | | | 高波 | 中国中医研究院广安门医院放射科,北京 100053 | | | 王映辉 | 中国中医研究院广安门医院针灸科,北京 100053 | | | 程谟库 | 中国中医研究院广安门医院放射科,北京 100053 | |
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| 中文摘要: |
| 目的 利用功能磁共振(fMRI) 观察针刺相邻穴位的大脑中枢反应,探讨穴位的相对特异性。方法 用盲法随机分别针刺10 例正常人左侧太冲、行间、内庭和邻近非经络假穴点,手针采用捻针和不捻针两种状态对比,利用1. 9 T MRI行全脑功能成像,用SPM 99 处理图像。结果 发现在4 穴上针刺时均产生了脑灰质结构的不同激活和抑制效应,太冲和行间激活和抑制区更相似,但太冲穴信号强度更强,内庭穴也可见较多的激活和抑制区,但与太冲穴相差较大,对照非经络假穴偶见激活灶,与太冲穴差异最大;各穴大脑抑制区也各有特点,但对照穴抑制区最为分散,并见双侧中央前回等皮层的抑制,各穴均见大脑边缘叶系统部分抑制。结论 不同穴位针刺时可能对脑皮层神经活动有较相对特异的作用。同经络相似神经支配的不同穴位脑中枢效应最相似,不同经络相邻近神经节段支配区的经穴有明显差异,而相邻近神经节段的对照穴大脑反应区与各穴位差异最大。 |
| 英文摘要: |
| Objective To compare the cerebral activation patterns following acupuncture between different acupoints usingfMRI. Methods Ten healthy subjects were investigated the cortical activation patterns during stimulation of three real(LIV2 , LIV3 and ST44) and one sham acupoints , they were punctured in a randomized and for the subjects blinded orderemploying rotating and non-rotating methods using a blocked paradigm on a 1. 9 T scanner. The functional data were ana-lyzed by using SPM 99. Results Both of fMRI signal increasing and signal decreasing areas were found in all four acupoints.However , they were in differential patterns , namely on LIV2 and LIV3 they were similar , but the density of signal increas-ing on LIV3 was the highest ; following by LIV2 , and then ST44 ; on ST44 were more different patterns from LIV3 ; on thesham point the increasing areas were sparsely and the areas of signal decreasing were the more dispersed , including motor area , S Ⅱ. On all four acupoints , the decreasing signal can be found in the limbic system. Conclusion Acupuncture seems toresult in relative specific cerebral activation patterns according to the neural innervations of acupoints and different meridians. |
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