| 罗良平,张缨,林志超,陈金城,王自能.恶性胸膜间皮瘤的CT诊断与鉴别诊断[J].中国医学影像技术,2005,21(8):1226~1229 |
| 恶性胸膜间皮瘤的CT诊断与鉴别诊断 |
| CT diagnosis and differential diagnosis of malignant pleural mesothelioma |
| 投稿时间：2005-04-20 修订日期：2005-05-08 |
| DOI： |
| 中文关键词: 胸膜疾病 体层摄影术,X线计算机 |
| 英文关键词:Pleural diseases Tomography, X-ray computed |
| 基金项目:中国博士后科研基金资助项目(2003033414)、广东省自然科学基金(010365)及全国留学人员科技活动择优资助项目(200302)。 |
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| 中文摘要: |
| 目的 探讨CT对恶性胸膜间皮瘤(MPM)的诊断与鉴别诊断价值。方法 回顾性分析119例胸膜病变(恶性79例,良性40例)患者的CT检查资料, 评价CT对良恶性胸膜病变尤其是MPM与其他良、恶性胸膜病变的鉴别诊断价值。结果 胸膜病变侵犯纵隔内结构、膈肌及胸壁等CT征象仅见于MPM与其他恶性胸膜病变(OMPD)。环绕形胸膜增厚在MPM、OMPD的发生率分别为52％、20.4％,良性胸膜病变(BPD)则无一例出现此征象。纵隔胸膜受累增厚在MPM组占92%,而OMPD和BPD分别为37%和5%,不同组别之间两两比较有显著性差异(P<0.001)。结节状胸膜增厚、胸膜增厚大于1 cm在MPM与BPD之间及OMPD与BPD之间的出现率有显著性差异(P<0.05),而在MPM与OMPD之间的出现率无显著性差异(P＞0.05)。 叶间胸膜不规则增厚在MPM与OMPD之间以及MPM与BPD之间的出现率有显著性差异(P<0.05),而在OMPD与BPD之间的出现率差异均无统计学意义(P＞0.05)。结论 结合胸膜病变的形态特点及其与纵隔的关系,有助于MPM与OMPD及BPD的鉴别诊断。 |
| 英文摘要: |
| Objective To explore the usefulness of CT in the diagnosis and differential diagnosis of malignant pleural mesothelioma (MPM). Methods The CT images of 119 patients with pleural disease (malignant 79, benign 40) proved pathologically were reviewed retrospectively and the differential diagnosis of benign and malignant pleural diseases especially MPM and other pleural diseases with CT was also evaluated. Results Chest wall or diaphragmatic or mediastinal invasion would be displayed only in MPM and other malignant pleural diseases (OMPD). The incidence of mediastinal pleural involvement and thickening in MPM, OMPD and benign pleural disease (BPD) was 52%, 20.4% and 0%, respectively. The incidence of rind-like pleural thickening in MPM, OMPD and BPD was 92%, 37% and 5%. Significant differences of incidence were found in each two groups (P<0.001). The incidence of nodular pleural thickening and pleural thickening more than 10 mm between MPM and BPD or between OMPD and BPD group had significant differences (P<0.05), otherwise, no significant differences were found between MPM and OMPD groups (P＞0.05). The incidence of interlobular pleural thickening irregularly between MPM and BPD or between MPM and OMPD groups had significant differences (P<0.05), otherwise, that between BPD and OMPD groups had no significant differences (P＞0.05). Conclusion In combination with the relationship to mediastinum, morphology characteristics of pleural lesions is helpful to differentiate MPM from OMPD and BPD. |
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