| 张建华,漆剑频,黄文华,张进华,宋金梅,肖明,吴进.多层螺旋CT灌注成像在脑星形细胞肿瘤术前分级中的价值[J].中国医学影像技术,2005,21(8):1183~1185 |
| 多层螺旋CT灌注成像在脑星形细胞肿瘤术前分级中的价值 |
| Multi-slice CT perfusion imaging in preoperative grading of astrocytic tumors |
| 投稿时间：2005-05-10 修订日期：2005-06-23 |
| DOI： |
| 中文关键词: 星形细胞肿瘤 灌注 体层摄影术,X线计算机 病理学 |
| 英文关键词:Astrocytic tumours Perfusion Tomography, X-ray computed Pathology |
| 基金项目: |
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| 中文摘要: |
| 目的 评价多层螺旋CT(MSCT)灌注成像在脑星形细胞肿瘤中的应用价值。方法 经手术及病理证实的脑星形细胞肿瘤共24例,行常规CT及MSCT灌注成像检查。原始图像经ADW 4.0工作站Perfusion 2软件处理,构建分析脑血容量(CBV)及表面通透性(PS)图像,计算平均CBV及PS值。结果 低级别星形细胞瘤组、间变性星形细胞瘤组及胶质母细胞瘤组最大CBV值分别为2.733±0.8274,4.755±0.4367,6.654±0.529;三组的PS值分别为16.668±0.5237,27.3524±0.8975,38.7452±0.328。三组间的CBF及PS值均有显著性差异,PS与CBF有明显正相关(r=0.832,P<0.01)。结论 MSCT灌注成像技术及灌注成像参数PS与CBV在术前评价星形细胞肿瘤的病理级别上有实用价值。 |
| 英文摘要: |
| Objective To evaluate multi-slice CT (MSCT) perfusion imaging in the preoperative assessment of histological grade in astrocytic tumors. Methods MSCT perfusion imaging was performed in 24 patients with astrocytic tumors, the scanning images were processed in ADW 4.0 workstation, the cerebral blood volume (CBV) and permeability surface (PS) values were calculated and the perfusion maps were analyzed. Results The maximum CBV value in low grade astrocytoma, anaplastic astrocytoma and glioblastoma was 2.733±0.8274, 4.755±0.4367, 6.654±0.529, respectively. The maximum PS value was 16.668±0.5237, 27.3524±0.8975, 38.7452±0.328, respectively. Statistically significant difference in cerebral blood flow and PS value existed between each group. A marked positive correlation was seen between CBV and PS value. Conclusion MSCT perfusion imaging and the parameters CBV&PS are useful in preoperative estimating the histological grade of astrocytic tumors. |
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