| 郑奎宏,马林,郭勇,郭行高,梁丽.颈髓软化扩散张量成像的初步研究[J].中国医学影像技术,2005,21(7):1003~1005 |
| 颈髓软化扩散张量成像的初步研究 |
| Preliminary study of MR diffusion tensor imaging on myelomalacia of the cervical spinal cord |
| 投稿时间：2005-04-18 修订日期：2005-05-23 |
| DOI： |
| 中文关键词: 脊髓疾病 磁共振成像 扩散 平面回波成像 |
| 英文关键词:Spinal cord diseases Magnetic resonance imaging Diffusion Echo-planar imaging |
| 基金项目: |
|
| 摘要点击次数: 2836 |
| 全文下载次数: 1043 |
| 中文摘要: |
| 目的 探讨颈髓软化扩散张量成像的可行性及临床应用价值。方法 采用平面回波成像技术对12例颈髓软化患者和36例健康志愿者行扩散张量成像(DTI)检查,并测量其表观扩散系数(ADC)值、各向异性分数(FA)值、第1本征值(λ1)、第2本征值(λ2)以及第3本征值(λ3)。结果 ADC图与FA图均能显示颈髓软化区之异常信号,其ADC值为(1512.44±450.16)×10-6mm2/s,FA值为(407.81±86.14)×10-3,λ1值为(2229.31±417.19)×10-6mm2/s,λ2值为(1416.01±379.05)×10-6mm2/s,λ3值为(1401.48±589.18)×10-6mm2/s,2λ1/(λ2＋λ3)值为1.67±0.23。颈髓软化患者病变区的ADC、λ1、λ2、λ3值明显高于正常组(P<0.05),其FA值与2λ1/(λ2＋λ3)值明显低于正常组(P<0.05),λ1与λ2、λ3值之间有显著性差异(P<0.05),λ1大于λ2与λ3。结论 DTI是一种显示颈髓软化的可靠检查手段,软化灶的各向同性扩散明显增高,其各向异性扩散明显减低。 |
| 英文摘要: |
| Objective To investigate the feasibility and clinical application of MR diffusion tensor imaging (DTI) in myelomalacia of the cervical spinal cord. Methods DTI of the cervical spinal cord was performed in 12 cases of myelomalacia and 36 healthy volunteers by using SE-EPI. The values of apparent diffusion coefficient (ADC), fractional anisotropy (FA), λ1, λ2, and λ3 were measured. Results Both ADC and FA maps were able to show abnormal signal intensities of myelomalacia. The average values of ADC, FA, λ1, λ2, λ3, and 2λ1/(λ2＋λ3) were (1512.44±450.16)×10-6mm2/s, (407.81±86.14)×10-3, (2229.31±417.19)×10-6mm2/s, (1416.01±379.05)×10-6mm2/s, (1401.48±589.18)×10-6mm2/s, and 1.67±0.23, respectively. The values of ADC, λ1, λ2, and λ3 of the myelomalacia increased evidently compared with those of normal cervical spinal cord (P<0.05), and the values of FA and 2λ1/(λ2＋λ3) decreased significantly compared with those of the control group (P<0.05). λ1 was significantly higher than λ2 or λ3 (P<0.05). Conclusion DTI is a reliable tool in demonstrating the myelomalacia of the cervical spinal cord, and myelomalacia has a markedly increased isotropic diffusion and evidently decreased anisotropic diffusion. |
| 查看全文 查看/发表评论 下载PDF阅读器 |
|
|
|
