| 王琦,徐荣天,徐克,王欣,卢涛,赵宇.胰腺多层螺旋CT灌注成像[J].中国医学影像技术,2005,21(5):754~756 |
| 胰腺多层螺旋CT灌注成像 |
| Multislice spiral CT perfusion imaging of pancreas |
| 投稿时间：2004-10-14 修订日期：2005-03-16 |
| DOI： |
| 中文关键词: 胰腺癌 体层摄影术,X线计算机 灌注,局部 |
| 英文关键词:Pancreatic cancer Tomography, X-ray computed Perfusion, regional |
| 基金项目: |
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| 中文摘要: |
| 目的 应用多层螺旋CT(MSCT)灌注扫描成像技术评价正常人胰腺与胰腺癌的血流动力学表现,并探讨其临床应用价值。方法 60例患者行多层螺旋CT胰腺灌注扫描,其中胰腺癌29例,正常胰腺31例。采用GE Lightspeed 16层MSCT ADW 4.1工作站,使用Perfusion-3软件包分析。分别测量血流量(BF)、血容量(BV)、平均通过时间(MTT)和毛细血管表面通透性(PS)。结果 正常组BF、BV、MTT及PS分别为:(176.54±76.18) ml/(100 mg·min)、(14.62±3.60) ml/100 mg、(7.02±3.09) s、(15.70±9.92) ml/(100 mg·min)。癌组分别为(74.89±91.50) ml/(100 mg·min)、(6.12±3.62) ml/100 mg、(10.38±5.31) s和(27.43±11.97) ml/(100 mg·min)。胰腺癌组和正常组的BF、BV、MTT和PS均有显著的统计学差异(BF、BV:P＜0.01; MTT、PS: P＜0.05)。结论 胰腺癌时的血流灌注与正常胰腺的血流灌注相比明显减少,MSCT灌注成像对胰腺癌血流变化的分析有一定临床价值。 |
| 英文摘要: |
| Objective To assess the characteristics of blood flow for normal pancreas and pancreatic cancer, and to discuss the value of MSCT perfusion technology. Methods The CT perfusion imaging were obtained using GE Lightspeed 16 slice spiral CT scanner in 29 patients with pancreatic cancer and 31 patients with normal pancreas tissue. Hemodynamic parameters including blood flow (BF),blood volume (BV), mean transmit time (MTT) and capillary vessel permeability surface (PS) were calculated. Results The BF, BV, MTT and PS of normal group were (176.54±76.18) ml/(100 mg·min), (14.62±3.60) ml/100 mg, (7.02±3.09) s, (15.70±9.92) ml/(100 mg·min), respectively, while those of pancreatic cancer group were (74.89±91.50) ml/(100 mg·min), (6.12±3.62) ml/100 mg, (10.38±5.31) s, (27.43±11.97) ml/(100 mg·min), respectively. Statistically significant differences were noted between pancreatic cancer and normal pancreas tissue with respect to BF,BV,MTT and PS (BF, BV, P＜0.01; MTT, PS, P＜0.05). Conclusion BF, BV of pancreatic cancer shorten significantly and MTT, PS increase markedly. It is significant that MSCT perfusion imaging analyze the chang of the blood flow for pancreatic cancer. |
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