张雪娇,程永清,李丽君,陈娜,刘银凤.超声微泡造影剂制备中乳化剂的选择[J].中国医学影像技术,2005,21(4):501~503 |
超声微泡造影剂制备中乳化剂的选择 |
Choice of emulsifier in the preparation of ultrasound contrast agent |
投稿时间:2004-09-15 修订日期:2005-03-16 |
DOI: |
中文关键词: 乳液聚合 乳化剂 单体转化率 超声造影剂,微泡 |
英文关键词:Emulsion polymerization Emulsifier Monomer conversion Ultrasound contrast agents, microbubbles |
基金项目:国家自然科学基金资助(30370579)。 |
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中文摘要: |
采用乳液聚合法对微泡超声造影剂的制备进行研究,重点对反应中所必需的乳化剂进行选择,并在此基础上讨论了乳化剂的用量及配比等对实验结果的影响。由本方法所制得的微泡粒径以2~8 μm的居多,浓度在9.51×109 /ml左右,单体转化率达到71%,有利于更进一步的研究。 |
英文摘要: |
The preparation of ultrasound contrast agent (UCA) by emulsion polymerization was studied. The study focus on the selection of the emulsifier which is necessary in the preparation. Then the effect of the emulsifier dose and ratio on the experimental Results was studied. The microbubbles were prepared by this method had a diameter of 2 to 8 μm, concentration of 9.51×1010/ml,and the monomer conversion rate was up to 71%, worthy of much more research. |
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