张燕燕,李欣欣,张松林,毛远,张卫方.99Tcm-MDP与18F-FDG显像对转移瘤探测价值的比较[J].中国医学影像技术,2005,21(3):465~468
99Tcm-MDP与18F-FDG显像对转移瘤探测价值的比较
Comparison of 99Tcm-
投稿时间:2004-11-07  修订日期:2004-12-07
DOI:
中文关键词:  99Tcm-MDP  18F-FDG  显像  转移瘤
英文关键词:99Tcm-MDP  18F-FDG  Imaging  Metastases
基金项目:
作者单位E-mail
张燕燕 北京大学第三医院核医学科,北京 100083 nmyy@vip.163.com 
李欣欣 北京大学第三医院核医学科,北京 100083  
张松林 北京大学第三医院核医学科,北京 100083  
毛远 北京大学第三医院核医学科,北京 100083  
张卫方 北京大学第三医院核医学科,北京 100083  
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中文摘要:
      目的 对恶性肿瘤患者同时行99Tcm-MDP、18F-FDG显像,以探索两种显像在检测转移瘤方面的能力与特点。方法 对43例经病理证实的恶性肿瘤患者及1例结核患者在1个月内,分别进行99Tcm-MDP、18F-FDG显像。结果 对骨转移瘤99Tcm-MDP与18F-FDG检出
英文摘要:
      Objective To compare the ability of detecting metastases for two methods, the patients who illed with malignant tumor underwent examinations of 99Tcm-MDP (technetium-99m methylene diphosphate) and 18F-FDG (18F-fluoro-2-deoxy-D-glucose) imaging during a month. Methods Forty-three patients with malignant tumor and a tuberculosis patient that were confirmed by pathology underwent examination of 99Tcm-MDP and 18F-FDG imaging. Results The sensitivity, specificity and accuracy for 99Tcm-MDP and 18F-FDG imaging were 77% and 77%, 67% and 91%, 73% and 82% to detect the bone metastases respectively. But total sensitivity (including bone and out of bone) was 84% for 18F-FDG imaging. It was 7% higher than 99Tcm-MDP. Conclusion 18F-FDG examination should be adopted earlier if there is some information to suggest malignant tumor but focus to occult. Because 99Tcm-MDP imaging may have whole body bone scan in one time and may discover bone metastases sensitively and economically, so that is a good method for patient who doubted bone metastases.
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