袁庆中,田建明,王培军,邵成伟,李树平,李跃华,任方远.CT灌注成像在肾肿瘤鉴别诊断中的应用价值[J].中国医学影像技术,2005,21(3):436~439
CT灌注成像在肾肿瘤鉴别诊断中的应用价值
Value of CT perfusion imaging in diagnosis of renal tumors
投稿时间:2004-11-10  修订日期:2005-02-26
DOI:
中文关键词:  体层摄影术,X线计算机  灌注成像  肾脏  肾脏肿瘤
英文关键词:Tomography, X-ray computed  Perfusion imaging  Kidney  Renal tumor
基金项目:
作者单位E-mail
袁庆中 上海长海医院放射科,上海 200433 yuanqz20032003@yahoo.com.cn 
田建明 上海长海医院放射科,上海 200433  
王培军 上海长海医院放射科,上海 200433  
邵成伟 上海长海医院放射科,上海 200433  
李树平 上海长海医院放射科,上海 200433  
李跃华 上海长海医院放射科,上海 200433  
任方远 上海长海医院放射科,上海 200433  
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中文摘要:
      目的 探讨CT灌注成像在肾肿瘤定性诊断和鉴别诊断方面的应用价值。方法 共收集肾癌15例,肾盂癌9例,肾错构瘤12例。以健康志愿者30例为对照组。进行肾区CT平描后选择经肾门层面或肿瘤的最大层面进行同层动态增强扫描,通过感兴趣区域分析法获得正常肾皮质、肾肿瘤组织和腹主动脉的时间-密度曲线,计算正常肾皮质和肾肿瘤组织的灌注值。结果 正常肾皮质的灌注值为(2.68±0.40) ml/(min·ml),肾癌灌注值为(1.51±0.68) ml/(min·ml),肾癌灌注值显著高
英文摘要:
      Objective To discuss the value of CT perfusion imaging in diagnosis of renal tumors. Methods By applying a nuclear medicine data processing technique to the time-density data obtained from dynamic CT, perfusion was performed in 30 cases of nomal renal cortex and 36 cases of renal tumors, including 15 cases of renal cell carcinoma (RCC), 9 cases of renal pelvic carcinoma (RPC), 12 cases of renal agiomyolipoma (RAML). A single level through the renal hili or renal tumor was scanned after the intravenous injection of 40-50 ml of contrast given at 5 ml/s. Thirty 0.5 s duration and 0.5 s interval scans were performed from 8 to 37 s after injection. Time-density curves were then drawn for both normal kidneys or renal tumor and aorta using regions of interest (ROIs). Perfusion was calculated as the peak upslope of the tissue time-density curve divided by peak aortic enhancement. Results Normal renal cortal perfusion was (2.68±0.40) ml/(min·ml). Perfusion of RCC, RPC and RAML were (1.51±0.68) ml/(min·ml),(0.80±0.11) ml/(min·ml) and (0.96±0.33) ml/(min·ml) respectively. Perfusion of RCC was much higher than that of other two renal tumors. Conclusion There is some value of CT perfusion imaging in diagnosis of renal tumors.
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