周青,郭瑞强,陈金玲,刘岚,郝力丹.小剂量多巴酚丁胺负荷下运用校正背向散射声学参数检测存活心肌[J].中国医学影像技术,2005,21(3):433~435
小剂量多巴酚丁胺负荷下运用校正背向散射声学参数检测存活心肌
Detection of viable myocardium by corrected integrated backscatter parameters under low dose dobutamine stress echocardiography
投稿时间:2004-11-12  修订日期:2005-01-04
DOI:
中文关键词:  多巴酚丁胺  超声心动描记术  背向散射  存活心肌
英文关键词:Dobutamine  Echocardiography  Integrated backscatter  Viable myocardium
基金项目:
作者单位E-mail
周青 武汉大学人民医院超声科,湖北 武汉 430060 michacal@163.com 
郭瑞强 武汉大学人民医院超声科,湖北 武汉 430060  
陈金玲 武汉大学人民医院超声科,湖北 武汉 430060  
刘岚 武汉大学人民医院超声科,湖北 武汉 430060  
郝力丹 武汉大学人民医院超声科,湖北 武汉 430060  
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中文摘要:
      目的 探讨在小剂量多巴酚丁胺负荷(LDDSE)下运用校正背向散射声学参数能否提高检测存活心肌的敏感性和特异性。方法 心肌梗死患者46例,按照PTCA术后室壁运动改善状况将心肌节段分为存活心肌组和非存活心肌组,比较2组在PTCA前LDDSE下的心肌背向散射指标。结果 LDDSE下存活心肌的CVIB及校正CVIB值均高于静息状态,而非存活心肌的CVIB与校正CVIB值在两种状态下无明显差异。以CVIB>5.0 dB和校正CVIB>3.8 dB作为判断存活心肌的标准,敏感性、
英文摘要:
      Objective To certificate whether the sensitivity and specificity of detecting viable myocardium could be enhanced by using corrected integrated backscatter indices (CVIB and phase-weighed CVIB) under low dose dobutamine stress echocardiography (LDDSE). Methods LDDSE was executed on 46 patients with myocardial infarction before percutaneous coronary angiography (PTCA). CVIB and corrected CVIB, as well as wall motion index (WMI), of anterior wall, anterior septum, inferior wall and posterior wall of the left ventricle were measured under LDDSE and baseline. Results CVIB and corrected CVIB of the viable myocardium under LDDSE were higher than that at baseline, but CVIB and corrected CVIB of the non-viable myocardium were not significantly different from baseline. Taking CVIB>5.0 dB and corrected CVIB>3.8 dB as the cut-off point, the sensitivity, specificity and accuracy of the integrated backscatter indices under LDDSE in predicting viable myocardium were 82.1% and 85.7%, 68.9% and 72.4%, 77.6% and 81.2%, respectively. Conclusion Integrated backscatter combined with LDDSE is valuable in detecting viable myocardium. Comparing to two-dimensional wall motion index, integrated backscatter index is superior with better objectivity and accuracy.
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