| 高阳,牛广明,韩晓东,郭冬玲,张颖.磁共振成像技术的联合应用诊断星形细胞瘤[J].中国医学影像技术,2005,21(3):358~360 |
| 磁共振成像技术的联合应用诊断星形细胞瘤 |
| Combined application of MR imaging technique in astrocytoma |
| 投稿时间：2004-12-20 修订日期：2005-01-18 |
| DOI： |
| 中文关键词: 磁共振成像 弥散 灌注 磁共振波谱学 星形细胞瘤 |
| 英文关键词:Magnetic resonance imaging Diffusion Perfusion Magnetic resonance spectroscopy Astrocytoma |
| 基金项目: |
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| 摘要点击次数: 2421 |
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| 中文摘要: |
| 目的 应用磁共振弥散加权成像(DWI)、灌注加权成像(PWI)及波谱成像(MRS),探讨ADC值、rCBV值和各代谢产物比值在术前评价星形细胞瘤组织学分级中的价值。方法 共收集了41例经病理证实的星形细胞瘤,进行DWI及MRS成像,增强后行PWI及普通增强扫描。获得DW、PW伪彩图和代谢产物曲线,利用分析软件包Function-Tool计算ADC值、rCBV值和NAA/Cr,Ch/Cr,NAA/Ch值。结果 高度恶性星形细胞瘤(21例)ADC值、rCBV值及NAA/Cr |
| 英文摘要: |
| Objective To evaluate the potential of ADC, rCBV and NAA/Cr, Ch/Cr, NAA/Ch in preoperative assessment of histologic grading of astrocytoma by means of diffusion weighted imaging(DWI), perfusion weighted imaging(PWI) and magnetic resonance spectroscopy (MRS). Methods MR imaging was performed in 41 patients with pathologically proven astrocytoma by using DWI, MRS and PWI. The perfusion and diffusion data were deconvoluted to a color map of ADC and rCBV. ADC, rCBV and NAA/Cr, Ch/Cr, NAA/Ch were obtained through Function-Tool. Results The ADC, rCBV and NAA/Cr, Ch/Cr, NAA/Ch in high-grade astrocytoma (21 cases) were (1.38±0.37) mm2/s (0.61-2.03 mm2/s), 4.04±1.75 (1.98-8.31), 0.68±0.25 (0.24-1.23), 4.87±1.89 (2.33-7.99) and 0.18±0.11 (0.06-0.47), respectively. The ADC, rCBV and NAA/Cr, Ch/Cr, NAA/Ch in low-grade astrocytoma (20 cases) were (1.63±0.30) mm2/s (1.08-2.13 mm2/s), 1.64±0.90 (0.23-3.58), 0.97±0.42 (0.46-2.30), 2.36±1.22 (1.14-6.38) and 0.45±0.36 (0.16-1.71), respectively. Conclusion DWI, PWI and MRS are very useful in preoperative predicting tumor grade of astrocytoma. |
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