| 范光明,郭启勇,解学乾,陈丽英,于涛,侯阳.造影剂量和注射流率对肝脏CT灌注成像影响的实验研究[J].中国医学影像技术,2005,21(1):14~17 |
| 造影剂量和注射流率对肝脏CT灌注成像影响的实验研究 |
| Influence of contrast agent's dose and injection rate on hepatic perfusion CT: an experimental study |
| 投稿时间：2004-09-15 修订日期：2004-10-26 |
| DOI： |
| 中文关键词: 体层摄影术,X线计算机 灌注 肝脏 定量 动物,实验 |
| 英文关键词:Tomography, X-ray computed Perfusion Liver Quantification Animals, laboratory |
| 基金项目: |
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| 中文摘要: |
| 目的探讨用斜率法进行肝脏CT灌注成像时造影剂量和注射流率对灌注参数的影响。方法 分别用0.5、1 ml/kg体重的造影剂量和3、5、7、9 ml/s的注射流率对6只犬进行肝脏灌注成像,计算肝动脉灌注量(HAP)、门脉灌注量(PVP)和肝动脉灌注指数(HPI)。结果 造影剂量为0.5 ml/kg体重时,3 ml/s流率与其他流率测得的HAP和PVP有显著性差异(P<0.05),HPI随着流率的增加而略有下降;造影剂量为1 ml/kg体重时,各种流率下的HAP和HPI均无显著性差异(P＞0.05),PVP先升高后降低。结论 用斜率法进行肝脏灌注成像时,造影剂量和注射流率对灌注参数有所影响。 |
| 英文摘要: |
| Objective To investigate the influence of various doses of contrast agent and injection rates on hepatic perfusion imaging using slope method. Methods Hepatic perfusion CT was performed in 6 dogs with different doses of contrast agent (0.5,1 ml/kg) and different injection rates(3,5,7,9 ml/s). Hepatic arterial perfusion (HAP), portal venous perfusion (PVP) and hepatic perfusion index (HPI) were calculated with special software.Results With the dose of 0.5 ml/kg of body weight, HAP and PVP at the injection rate of 3 ml/s were significantly lower than that of other injection rates (P<0.05). HPI dropped slightly with increasing injection rate.With the dose of 1 ml/kg of body weight, no significant difference was found in HAP and HPI at different injection rates (P＞0.05). PVP rose at first and then dropped.Conclusion When slope method is used in hepatic perfusion imaging, the dose of contrast agent and injection rate have some influence on hepatic perfusion parameters. |
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