康宁,俎栋林,张宏杰.自旋密度ρ、弛豫时间T1和T2定量磁共振成像[J].中国医学影像技术,2004,20(12):1944~1947
自旋密度ρ、弛豫时间T1和T2定量磁共振成像
Quantitative magnetic resonance imaging of spin density ρ,relaxation times T1 and T2
投稿时间:2004-10-04  
DOI:
中文关键词:  磁共振成像  线性回归  定量图像  ρ-map  T2-map  T1-map
英文关键词:Magnetic resonance imaging  Linear regression  Quantitative image  ρ-map  T2-map  T1-map
基金项目:
作者单位
康宁 北京大学重离子物理所,北京大学医学物理和工程北京市重点实验室,北京 100871 
俎栋林 北京大学重离子物理所,北京大学医学物理和工程北京市重点实验室,北京 100871 
张宏杰 1.北京大学重离子物理所,北京大学医学物理和工程北京市重点实验室,北京 100871
2.海军总医院 
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中文摘要:
      目的 研究定量MR图像可能的临床应用和借助于计算机自动认读图像的可行性。方法 利用最基本的磁共振参数,自旋密度ρ、弛豫时间T1、T2以及临床自旋回波序列、线性回归拟合方法得到定量maps,以探索所执行的路线。结果 分别用自旋双回波序列和自旋快回波序列采集混合加权图像数据,对其中任一套数据进行后处理,都成功得到了定量的自旋密度ρ-map、弛豫时间T2-map和T1-map。结论 上述两种采集方法中,快自旋回波采集可减少采集时间,且效果比较理想。用一个子序列扫描获得一套数据,同时处理出三个参数的maps是可行的。
英文摘要:
      Objective To search for possible applications of quantitative image and computer aided automatic identifying image of MRI. Methods Using the basic MRI parameters such as spin-density ρ,relaxation time T2 and T1, and the common clinic SE sequences and LR fitting method, quantitative maps were obtained, and the feasibility of pathway was described. Results Two sets of data were collected by twin echo sequence and FSE sequence. Each set could be successfully processed and spin-density ρ-map、relaxation time T2-map and T1-map could be obtained quantitatively. Conclusion Comparing with twin echo sequence, fast spin-echo sequence is of time saving with good effect. The method of scanning one subsequence, obtaining one set of data and three parameters' maps at one time is feasible.
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