| 谢启东,冯炎,沈瑾.肝硬化患者甲状腺体积、甲状腺激素改变与血流动力学变化的关系[J].中国医学影像技术,2004,20(12):1862~1864 |
| 肝硬化患者甲状腺体积、甲状腺激素改变与血流动力学变化的关系 |
| The relation between changes of thyroid volume, thyroid hormone and hemodynamic alterations in liver cirrhosis |
| 投稿时间：2004-06-12 |
| DOI： |
| 中文关键词: 肝硬化 甲状腺 超声检查 甲状腺激素 血流动力学 |
| 英文关键词:Cirrhosis Thyroid Ultrasonography Thyroid hormones Hemodynamics |
| 基金项目: |
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| 中文摘要: |
| 目的 评估肝硬化患者甲状腺体积、甲状腺激素的变化与其血流动力学改变的关系。方法 对45例肝硬化患者及健康人13例,分别测量甲状腺体积、甲状腺下动脉的阻力指数(RI)和搏动指数(PI),血清FT3、FT4、TSH浓度;同时测量门静脉内径、血流速度、血流量以及肝动脉、肾动脉和脾动脉RI。结果 在肝硬化Child C级患者中,甲状腺体积增大(P<0.05),FT3降低(P<0.05),TSH 和 FT4各组间无明显差别;肝硬化患者PI、RI 升高 (PI: 1.01 ± 0.15 vs 0.81 ± 0.11; RI: 0.62 ± 0.05 vs 0.53 ± 0.04; P<0.01),并与FT3负相关 (P<0.05), 与肝、脾、肾动脉RI呈正相关 (P<0.01)。结论 甲状腺激素与肝硬化患者的血流动力学改变有关,其中 FT3减低可能起重要作用。 |
| 英文摘要: |
| Objective To investigate the relation between changes of thyroid volume, thyroid hormone and hemodynamic alterations in patients with liver cirrhosis. Methods Thyroid volume, FT3, FT4, TSH, resistance index (RI) and pulsatility index (PI) in the inferior thyroid artery in 45 cirrhotic patients of different aetiologies and Child class and 13 healthy subjects were measured. Portal vein velocity, flow, diameter and hepatic, splenic, and renal arterial resistance indices were also evaluated. Results Thyroid volume increased in Child-C patients (P<0.05). FT3 decreased in cirrhotic patients (P<0.05), TSH and FT4 were not different. PI and RI increased in cirrhotic patients (PI: 1.01 ± 0.15 vs 0.81 ± 0.11, RI: 0.62 ± 0.05 vs 0.53 ± 0.04, P<0.01) and were inversely correlated with FT3 (P<0.05), and directly correlated with hepatic, splenic and renal resistance indices (P<0.01). Conclusion Thyroid is involved in the hemodynamic alterations of cirrhosis, which may be a result of reduction in FT3. |
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