| 赵静霞,刘青蕊,李来有,李如迅,贺丹.急性脑梗死治疗前后脑血流动力学改变:CT灌注成像[J].中国医学影像技术,2004,20(12):1839~1841 |
| 急性脑梗死治疗前后脑血流动力学改变:CT灌注成像 |
| Cerebral hemodynamics before and after treatment of acute cerebral infarction: CT perfusion imaging |
| 投稿时间：2004-05-10 |
| DOI： |
| 中文关键词: 急性期脑梗死 血流动力学 体层摄影术,X线计算机 |
| 英文关键词:Acute cerebral infarction Hemodynamics Tomography, X-ray computed |
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| 中文摘要: |
| 目的 观测急性脑梗死治疗前后多层螺旋CT灌注成像(MSCTPI)的脑血流动力学指标变化。方法 31例发病6~22 h的临床诊断为急性脑梗死的患者,分别于发病第1天,第7~21天行常规CT平扫及MSCTPI检查。结果 治疗后病变区血流量、血容量较治疗前均增加(t=4.57, P<0.01; t=3.81, P<0.01);达峰时间较治疗前缩短(t=3.62, P<0.01)。结论 急性脑梗死治疗前后CT灌注成像的脑血流动力学指标变化明显,提示早期干预具有治疗效果。 |
| 英文摘要: |
| Objective To observe and measure the changes of cerebral hemodynamics before and after treatment of acute cerebral infarction. Methods Thirty-one patients with acute infarction diagnosed clinically from 6 to 22 h after the onset of symptoms, underwent routine CT and multislice CT perfusion imaging (MSCTPI) exmined after onset 1 day, 7-21 day, respectively. In the perfusion images, the cerebral blood flow (CBF), cerebral blood volume (CBV), and time to peak (TP) of patients were measured respectively within the specific regions of interest (ROI) of the brain, and quantitative analysis was performed. Results CBF, CBV on ischemic lesion of patients increased after treatment compared with that before treatment (t=4.57,P<0.01; t=3.81,P<0.01). TP of the patients after treatment was shorten compared with that before treatment (t=3.62, P<0.01). Conclusion Significant changes of cerebral hemodynamics exist before and after treatment of acute cerebral infarction, indicting that early intervention is effective in the treatment of acute cerebral infarction. |
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